The concept of reductive radical-polar crossover (RRPCO) reactions has recently emerged
as a valuable and powerful tool to overcome limitations of both radical and traditional polar …

The metal-hydride hydrogen atom transfer (MHAT) reaction plays an important role in the
field of natural product synthesis. MHAT, as a powerful method, has been employed by …

The catalytic enantioselective synthesis of tetrahydrofurans, which are found in the
structures of many biologically active natural products, via a transition-metal-catalyzed …

Daphnezomines A and B are structurally unusual Daphniphyllum alkaloids that contain a
unique aza-adamantane core skeleton. Herein, a modular approach to these alkaloids is …

A hydrogen atom transfer (HAT)-initiated Dowd–Beckwith rearrangement reaction was
developed, which enables the efficient assembly of diversely functionalized polyquinane …

The power of cation-initiated cyclizations of polyenes for the synthesis of polycyclic
terpenoids cannot be overstated. However, a major limitation is the intolerance of many …

An efficient and scalable total synthesis of (−)-triptonide is accomplished based on a metal-
catalyzed hydrogen atom transfer (MHAT)-initiated radical cyclization. During the …

Synthesis of a potent inhibitor of bacterial protein synthesis, pleuromutilin, is described.
Assembly of the critical cyclooctane fragment relies on an oxidative ring-expansion, and …

Herein we report a one-step, catalytic, Markovnikov-selective, and scalable method for the
synthesis of saturated sulfur heterocycles, which are found in the structures of …

The complex and diverse molecular architectures along with broad biological activities of ent-
kauranoids natural products make them an excellent testing ground for the invention of …