[HTML][HTML] Epigenetic regulation of the histone-to-protamine transition during spermiogenesis
J Bao, MT Bedford - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
In mammals, male germ cells differentiate from haploid round spermatids to flagella-
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
Essential role of histone replacement and modifications in male fertility
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …
distinct morphological change, and the protamines replace the core histones to facilitate …
The dynamics and regulation of chromatin remodeling during spermiogenesis
SL Hao, FD Ni, WX Yang - Gene, 2019 - Elsevier
The functional sperm is the key factor for species continuation. The process
spermatogenesis, to produce mature sperm is quite complex. It begins with the proliferation …
spermatogenesis, to produce mature sperm is quite complex. It begins with the proliferation …
Insights into role of bromodomain, testis-specific (Brdt) in acetylated histone H4-dependent chromatin remodeling in mammalian spermiogenesis
S Dhar, A Thota, MRS Rao - Journal of Biological Chemistry, 2012 - ASBMB
Mammalian spermiogenesis is of considerable biological interest especially due to the
unique chromatin remodeling events that take place during spermatid maturation. Here, we …
unique chromatin remodeling events that take place during spermatid maturation. Here, we …
Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development
S Yassine, J Escoffier, G Martinez… - Mhr: Basic science of …, 2015 - academic.oup.com
We recently identified the DPY19L2 gene as the main genetic cause of human
globozoospermia. Non-genetically characterized cases of globozoospermia were …
globozoospermia. Non-genetically characterized cases of globozoospermia were …
Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements
Background Linker histones establish and maintain higher-order chromatin structure. Eleven
linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific …
linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific …
[HTML][HTML] DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers
SM Khamis, RA Jones, ATC Johnson, G Preti, J Kwak… - AIP advances, 2012 - pubs.aip.org
We have explored the abilities of all-electronic DNA-carbon nanotube (DNA-NT) vapor
sensors to discriminate very similar classes of molecules. We screened hundreds of DNA …
sensors to discriminate very similar classes of molecules. We screened hundreds of DNA …
Multi-target aptamer assay for endocrine-disrupting phthalic acid ester panel screening in plastic leachates
A multi-target aptamer assay was developed as a phthalic acid ester (PAE) panel to screen
selected PAEs in plastic leachate samples. The panel comprises 13 PAEs (PAE-13), namely …
selected PAEs in plastic leachate samples. The panel comprises 13 PAEs (PAE-13), namely …
Mapping of post-translational modifications of spermatid-specific linker histone H1-like protein, HILS1
In mammalian spermiogenesis, haploid round spermatids undergo dramatic biochemical
and morphological changes and transform into motile mature spermatozoa. A majority of the …
and morphological changes and transform into motile mature spermatozoa. A majority of the …
Mapping of post-translational modifications of transition proteins, TP1 and TP2, and identification of protein arginine methyltransferase 4 and lysine methyltransferase …
In a unique global chromatin remodeling process during mammalian spermiogenesis, 90%
of the nucleosomal histones are replaced by testis-specific transition proteins, TP1, TP2, and …
of the nucleosomal histones are replaced by testis-specific transition proteins, TP1, TP2, and …