In the past 40 years, liver transplantation has evolved from a high-risk procedure to one that
offers high success rates for reversal of liver dysfunction and excellent patient and graft …

Natural killer (NK) cells are highly heterogeneous innate lymphocytes with a diverse
repertoire of phenotypes and functions. Their role in organ transplantation has been poorly …

Human intestinal transplantation often results in long-term mixed chimerism of donor and
recipient blood in transplant patients. We followed the phenotypes of chimeric peripheral …

Highlights•Rare HSPCs are found in blood and tissues such as spleen, liver, and
lung.•Extramedullary HSPCs contribute to blood formation under stress conditions.•The …

Mesenchymal stem cells (MSC) are present in the bone marrow, from where they are
thought to migrate through the blood stream to the sites of injury. However, virtually all …

Blood chimerism has been reported sporadically among visceral transplant recipients,
mostly in association with graft-vs-host disease (GVHD). We hypothesized that a higher …

In the immunocompromised setting, recipients of solid-organ or hematopoietic stem-cell
transplants carry an increased risk of post-transplant lymphoproliferative disorder (PTLD) …

Abstract γδ T cells are heterogeneous lymphocytes located in various tissues. However, a
systematic and comprehensive understanding of the origins of γδ T cell heterogeneity and …

A comparison of pre-clinical transplant models and of solid organs transplanted in routine
clinical practice demonstrates that the liver is most amenable to the development of …

The use of immunosuppressive medications for solid organ transplantation is associated
with cardiovascular, metabolic, and oncologic complications. On the other hand, the …