Biomarkers are described as characteristics that provide information about biological conditions whether normal or pathological. Detection of biomarkers at the earliest stage of …
Abstract Peptide Nucleic Acids (PNAs) are the DNA/RNA analogues in which sugar- phosphate backbone is replaced by N-2-aminoethylglycine repeating units. PNA contains …
A Saadati, S Hassanpour, M de la Guardia… - TrAC Trends in …, 2019 - Elsevier
The analogs of DNA are unique biomedical tools that are broadly utilized to develop different types of biosensors. Peptide nucleic acids (PNA) are an individual and notable …
Clinical diagnostic tests should be quick, reliable, simple to perform, and affordable for diagnosis and treatment of diseases. In this regard, owing to their novel properties …
M Tian, M Qiao, C Shen, F Meng, LA Frank… - Applied Surface …, 2020 - Elsevier
DNA probe-based biosensors have been widely developed for detecting a range of analytes. However, the DNA probe-based sensors suffer from many problems, such as long …
MicroRNAs (miRNAs) are a family of non-protein-coding, endogenous, small RNAs. They are a group of gene regulators that function mainly by binding the 3′ untranslated regions …
Cancer is a genetic disease induced by mutations in DNA, in particular point mutations in important driver genes that lead to protein malfunctioning and ultimately to tumorigenesis …
C Briones, M Moreno - Analytical and bioanalytical chemistry, 2012 - Springer
Nucleic acid biosensors have a growing number of applications in genetics and biomedicine. This contribution is a critical review of the current state of the art concerning the …
Peptide nucleic acids (PNA) are synthetic analog of DNA with a repeating N-(2-aminoethyl)- glycine peptide backbone connected to purine and pyrimidine nucleobases via a linker …