Enforcement of postzygotic species boundaries in the fungal kingdom

JY Chou, PC Hsu, JY Leu - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
Understanding the molecular basis of speciation is a primary goal in evolutionary biology.
The formation of the postzygotic reproductive isolation that causes hybrid dysfunction …

Protein moonlighting by a target gene dominates phenotypic divergence of the Sef1 transcriptional regulatory network in yeasts

PC Hsu, TC Lu, PH Hung, JY Leu - Nucleic Acids Research, 2024 - academic.oup.com
Transcriptional rewiring generates phenotypic novelty, acting as an important mechanism
contributing to evolutionary development, speciation, and adaptation in all organisms. The …

Experimental approaches to study evolutionary cell biology using yeasts

M Natalino, M Fumasoni - Yeast, 2023 - Wiley Online Library
The past century has witnessed tremendous advances in understanding how cells function.
Nevertheless, how cellular processes have evolved is still poorly understood. Many studies …

Multifarious Translational Regulation during Replicative Aging in Yeast

T Zhao, A Chida, Y Shichino, D Choi, M Mizunuma… - Journal of Fungi, 2022 - mdpi.com
Protein synthesis is strictly regulated during replicative aging in yeast, but global
translational regulation during replicative aging is poorly characterized. To conduct …

Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network

PC Hsu, YH Cheng, CW Liao, RRR Litan, YT Jhou… - EMBO …, 2023 - embopress.org
The discrete steps of transcriptional rewiring have been proposed to occur neutrally to
ensure steady gene expression under stabilizing selection. A conflict‐free switch of a …

Response of alcohol fermentation strains, mixed fermentation and extremozymes interactions on wine flavor

LZ Zhao, J Chen, XY Wei, B Lin, FJ Zheng… - Frontiers in … - frontiersin.org
Winemaking, one of the ancient technologies, is simply the process of converting sugar into
alcohol through a complex biochemical reaction. The process of winemaking involves a …

Rapid compensatory evolution by secondary perturbation of a primary disrupted transcriptional network

PC Hsu, YH Cheng, CW Liao, YT Jhou, FJG Opoc… - bioRxiv, 2022 - biorxiv.org
The discrete steps of transcriptional rewiring have been proposed to occur neutrally to
ensure steady gene expression under stabilizing selection over long time-scales, especially …