Cryptic genetic variation (CGV) is invisible under normal conditions, but it can fuel evolution
when circumstances change. In theory, CGV can represent a massive cache of adaptive …

Heat‐shock proteins (Hsps) and their cognates are primary mitigators of cell stress. With
increasingly severe impacts of climate change and other human modifications of the …

A genome-scale genetic interaction map was constructed by examining 5.4 million gene-
gene pairs for synthetic genetic interactions, generating quantitative genetic interaction …

A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to
reflect the most recent research This updated edition of the widely read Evolution in Four …

Robustness is characterized by the invariant expression of a phenotype in the face of a
genetic and/or environmental perturbation. Although phenotypic variance is a central …

Neurons can produce action potentials with high temporal precision. A fundamental issue is
whether, and how, this capability is used in information processing. According to the 'cell …

Living things are unimaginably complex, yet they have withstood a withering assault of
harmful influences over several billion years. These influences include cataclysmic changes …

Robustness is the invariance of phenotypes in the face of perturbation. The robustness of
phenotypes appears at various levels of biological organization, including gene expression …

Cryptic genetic variation is the dark matter of biology: it is variation that is not normally seen,
but that might be an essential source of physiological and evolutionary potential. It is …

Extreme environments are closely associated with phenotypic evolution, yet the
mechanisms behind this relationship are poorly understood. Several themes and …