Neuronal migration is a fundamental process in central nervous system (CNS) development.
The assembly of functioning neuronal circuits relies on neuronal migration occurring in the …

Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG)
progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward …

Most neurons migrate with an elongated,“bipolar” morphology, extending a long leading
process that explores the environment. However, when immature projection neurons enter …

Reelin is a large extracellular matrix protein with relevant roles in mammalian central
nervous system including neurogenesis, neuronal polarization and migration during …

Understanding the molecular networks controlling ectopic lipid deposition, glucose
tolerance, and insulin sensitivity is essential to identifying new pharmacological approaches …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and 10–
20% of patients with NAFLD progress to nonalcoholic steatohepatitis (NASH) with a high risk …

Nonalcoholic fatty liver disease (NAFLD) contributes to the pathogenesis of type 2 diabetes
and cardiovascular disease, and patients with nonalcoholic steatohepatitis (NASH) are also …

Precise control of neuronal migration is required for the laminar organization of the
neocortex and critical for brain function. We previously reported that the acute disruption of …

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are
emerging as leading causes of liver disease worldwide and have been recognized as one of …

Background Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body
glucose and insulin homeostasis and the accumulation of ectopic lipids. The Warburg effect …