Synthesis, spectral characteristics, and molecular structure of 2-(2,4-dichlorophenyl)-6-(2-methoxybenzyl)-4-(trichloromethyl)-4H-1,3,5-oxadiazine

PV Zadorozhnii, VV Kiselev, OO Hrek… - Structural Chemistry, 2022 - Springer
This work reports on the synthesis of a new member of the 1, 3, 5-oxadiazine series—2-(2, 4-
dichlorophenyl)-6-(2-methoxybenzyl)-4-(trichloromethyl)-4 H-1, 3, 5-oxadiazine. The target …

Synthesis of 6‐RN‐aryl‐4‐(trichloromethyl)‐4H‐1,3,5‐oxadiazin‐2‐amines based on N‐(2,2,2‐trichloro‐1‐(3‐R‐thioureido)ethyl)carboxamides: Their spectral …

YR Lomynoha, PV Zadorozhnii… - Journal of …, 2024 - Wiley Online Library
In this work, we report the synthesis of a series of new 4 H‐1, 3, 5‐oxadiazine derivatives.
The method of their production is based on the dehydrosulfurization reaction of N‐(2, 2, 2 …

Synthesis and spectral characteristics of N-(2,2,2-trichloro-1-((5-(R-amino)-1,3,4-thiadiazol-2-yl)amino)ethyl)carboxamides

VV Pavlova, PV Zadorozhnii, AB Ryabitsky… - Synthetic …, 2024 - Taylor & Francis
In this paper, we reported the development of an efficient and highly productive synthetic
protocol for preparing new 2, 5-diamino-1, 3, 4-thiadiazole derivatives functionalized with N …

[PDF][PDF] Synthesis, Anti-Inflammatory Activity and Molecular Docking Studies of 1, 4, 5, 6-Tetrahydropyrimidine-2-Carboxamides

VY Horishny, PV Zadorozhnii, IV Horishnia… - Pharmaceutical …, 2020 - ps.tbzmed.ac.ir
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly
used drugs in the world. The widespread use of NSAIDs is associated with a number of …

Synthesis, Spectral Characteristics, and Molecular Docking Studies of 2,4-Dichloro-N-(2,2,2-trichloro-1-((5-(phenylamino)-1,3,4-thiadiazol-2-yl)amino)ethyl) …

VV Pavlova, PV Zadorozhnii, VV Kiselev… - Chemistry …, 2022 - mdpi.com
Derivatives of 1, 3, 4-thiadiazole are of great interest for scientific and practical human
activities as biologically active substances, dyes, components for creating semiconductors …

Design, Synthesis, Characterization and Antioxidant activity of Novel Benzothiazole and Coumarin based 6-(3, 5-dimethylpyrazol-1-yl) pyridazin-3-one Derivatives

RV Gadhave, BS Kuchekar - Research Journal of Pharmacy …, 2020 - indianjournals.com
The present work describes biological evaluation of target molecules designed by molecular
docking with 4h1j protein using Autodock Vina docker. Designed novel benzothiazole and …

[PDF][PDF] Pavlo V. Zadorozhnii, Vadym V. Kiselev, Valeriia V. Pavlova

AV Kharchenko, OV Okhtina - 2021 - biointerfaceresearch.com
This study has comparatively evaluated the degree of affinity of N-(5-morpholino-2-
arylimidazo [2, 1-b][1, 3, 4] thiadiazol-6-yl) carboxamides 2a-f and 6-(4-isopropylphenyl)-2-(4 …