Folic acid and the prevention of birth defects: 30 years of opportunity and controversies

KS Crider, YP Qi, LF Yeung, CT Mai… - Annual review of …, 2022 - annualreviews.org
For three decades, the US Public Health Service has recommended that all persons capable
of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects …

[HTML][HTML] Folate and vitamin B12 usual intake and biomarker status by intake source in United States adults aged≥ 19 y: NHANES 2007–2018

Y Zhou, A Wang, LF Yeung, YP Qi, CM Pfeiffer… - The American Journal of …, 2023 - Elsevier
Background Folate and vitamin B12 are important biomarkers of nutritional status of
populations. Objectives This study aims to estimate folate and vitamin B12 usual intakes …

Complete genome analysis of Bacillus subtilis derived from yaks and its probiotic characteristics

A Li, M Wang, Y Zhang, Z Lin, M Xu, L Wang… - Frontiers in Veterinary …, 2023 - frontiersin.org
Probiotics have attracted attention due to their multiple health benefits to the host. Yaks
inhabiting the Tibetan plateau exhibit excellent disease resistance and tolerance, which may …

Relationship of dietary natural folate and synthetic folic acid co-exposure patterns with biological aging: findings from NHANES 2003–2018

J Zhang, XY Wang, S Yang, X Xie, SJ Pan, XQ Xu… - Food & Function, 2024 - pubs.rsc.org
Background: The mandatory folic acid fortification program in the United States has
inevitably exposed most Americans to both natural folate and synthetic folic acid. We aim to …

Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition

RZ Guo, J Li, SK Pan, MY Hu, LX Lv… - The American Journal …, 2024 - World Scientific
Acute kidney injury (AKI) is a major public health problem worldwide that still lacks effective
treatments. Recent studies have suggested that ferroptosis is a key mediator of AKI due to its …

Association between RBC folate and diabetic nephropathy in Type2 diabetes mellitus patients: a cross-sectional study

P Yu, Y Ji, H Wang, K Liu - Scientific Reports, 2024 - nature.com
Folates play a crucial role as cofactors in metabolic pathways, influencing biological
methylation and nucleotide synthesis, which has a significant impact on overall health and …

[HTML][HTML] Distribution and correlates of plasma folate, vitamin B12, and homocysteine in a sample of low-income minority children aged 6 months to 9 years in the US

Y Chen, X Che, R Raghavan - Precision Nutrition, 2024 - journals.lww.com
Background: Precision nutrition emphasizes tailoring dietary requirements across
populations and life stages. Optimal folate and vitamin B12 levels are important for normal …

One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: Results from National Health and Nutrition Examination Survey …

AK Bozack, D Khodasevich, JC Nwanaji-Enwerem… - medRxiv, 2025 - medrxiv.org
Background: One-carbon metabolism (OCM), a biochemical pathway dependent on
micronutrients including folate and vitamin B12, plays an essential role in aging-related …

Secular trends in folate and vitamin B12 status in over half a million Norwegian adults between 2000 and 2019

SH Quamme - 2023 - duo.uio.no
Background: Folate (vitamin B9) and vitamin B12 (B12) are essential nutrients for
maintaining normal haematological and neurological function as well as preventing birth …

Estimating the serum folate concentration that corresponds to the red blood cell folate concentration threshold associated with optimal neural tube defects prevention …

A Fothergill, KS Crider, CE Rose, B Bose… - The American Journal of …, 2023 - Elsevier
Background RBC folate concentrations are monitored at the population level, with a
recommended threshold for optimal neural tube defect (NTD) prevention. A corresponding …