PAMAM dendrimer‐based nanodevices for nuclear medicine applications

T Xiao, D Li, X Shi, M Shen - Macromolecular Bioscience, 2020 - Wiley Online Library
Nuclear medicine, involving nuclear medicine imaging and radiotherapy (RT), has become
a mainstay of theranostics in the field of nanomedicine and several examples have been …

Moving into the next era of PET myocardial perfusion imaging: introduction of novel 18F-labeled tracers

RA Werner, X Chen, SP Rowe, C Lapa… - … International Journal of …, 2019 - Springer
The heart failure epidemic continues to rise with coronary artery disease as one of its main
causes. Novel concepts for risk stratification to guide the referring cardiologist towards …

[HTML][HTML] Bioaccumulation and in vivo fate of toxic benzylalkyldimethylammonium chloride in rats via the radiotracer analysis

JE Park, SH Ryu, S Ito, MK Song, EJ Gu, H Shin… - Chemosphere, 2023 - Elsevier
Benzylalkyldimethylammonium chloride (BAC), a quaternary ammonium compound (QAC),
is utilized in industrial and biomedical applications for antimicrobial purposes. Since the …

Quantitative in vivo mapping of myocardial mitochondrial membrane potential

NM Alpert, N Guehl, L Ptaszek, M Pelletier-Galarneau… - PloS one, 2018 - journals.plos.org
Background Mitochondrial membrane potential (ΔΨ m) arises from normal function of the
electron transport chain. Maintenance of ΔΨ m within a narrow range is essential for …

Theranostic in GLP-1R molecular imaging: challenges and emerging opportunities

Y Xie, Y Wang, W Pei, Y Chen - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Theranostic in nuclear medicine combines diagnostic imaging and internal irradiation
therapy using different therapeutic nuclear probes for visual diagnosis and precise …

Synthesis and Biological Evaluation of 99mTc(I) Tricarbonyl Complexes Dual-Targeted at Tumoral Mitochondria

D Figueiredo, C Fernandes, F Silva, E Palma… - Molecules, 2021 - mdpi.com
For effective Auger therapy of cancer, the Auger-electron emitters must be delivered to the
tumor cells in close proximity to a radiosensitive cellular target. Nuclear DNA is considered …

Dendrimer-based contrast agents for PET imaging

L Zhao, X Shi, J Zhao - Drug Delivery, 2017 - Taylor & Francis
Positron emission tomography (PET) imaging offers physiological and biological information
through the in vivo distribution of PET agents for disease diagnosis, therapy monitoring and …

Ultrasensitive detection of malignant melanoma using PET molecular imaging probes

A Pyo, DY Kim, H Kim, D Lim… - Proceedings of the …, 2020 - National Acad Sciences
Malignant melanoma has one of the highest mortality rates of any cancer because of its
aggressive nature and high metastatic potential. Clinical staging of the disease at the time of …

Development and implementation of ISAR, a new synthesis platform for radiopharmaceutical production

C Frank, G Winter, F Rensei, V Samper… - EJNMMI …, 2019 - Springer
Background PET radiopharmaceutical development and the implementation of a production
method on a synthesis module is a complex and time-intensive task since new synthesis …

Scalable droplet-based radiosynthesis of [18 F] fluorobenzyltriphenylphosphonium cation ([18 F] FBnTP) via a “numbering up” approach

Y Lu, J Collins, KS Lin, RM van Dam - Lab on a Chip, 2024 - pubs.rsc.org
The [18F] fluorobenzyltriphenylphosphonium cation ([18F] FBnTP) has emerged as a highly
promising positron emission tomography (PET) tracer for myocardial perfusion imaging …