Insights into the role of renal biopsy in patients with T2DM: a literature review of global renal biopsy results

X Tong, Q Yu, G Ankawi, B Pang, B Yang, H Yang - Diabetes Therapy, 2020 - Springer
Introduction Renal biopsy performed in patients with type 2 diabetes mellitus (T2DM) for
atypical or suspected diabetic kidney disease (DKD) reveals one of three possibilities …

Kidney biopsy in type 2 diabetic patients: critical reflections on present indications and diagnostic alternatives

D Santoro, M Torreggiani, V Pellicanò… - International Journal of …, 2021 - mdpi.com
Roughly 3% of patients worldwide with a new diagnosis of type 2 diabetes mellitus (T2DM)
already have an overt nephropathy at diagnosis and about 20–30% of the remaining ones …

The level of serum albumin is associated with renal prognosis in patients with diabetic nephropathy

J Zhang, R Zhang, Y Wang, H Li, Q Han… - Journal of diabetes …, 2019 - Wiley Online Library
Objective. Although hypoalbuminemia is frequently found in most patients with diabetic
nephropathy (DN), its relationship to the severity and progression of DN remains largely …

TLR9 regulates NLRP3 inflammasome activation via the NF-kB signaling pathway in diabetic nephropathy

J Shen, Z Dai, Y Li, H Zhu, L Zhao - Diabetology & metabolic syndrome, 2022 - Springer
Abstract Background Toll-like receptors (TLRs) are critical sensors for the conservation of
bacterial molecules and play a key role in host defense against pathogens. The effect of …

[HTML][HTML] Causal knowledge graph construction and evaluation for clinical decision support of diabetic nephropathy

K Lyu, Y Tian, Y Shang, T Zhou, Z Yang, Q Liu… - Journal of Biomedical …, 2023 - Elsevier
Background Many important clinical decisions require causal knowledge (CK) to take action.
Although many causal knowledge bases for medicine have been constructed, a …

Metabolic and genetic response to probiotics supplementation in patients with diabetic nephropathy: a randomized, double-blind, placebo-controlled trial

A Mafi, G Namazi, A Soleimani, F Bahmani… - Food & function, 2018 - pubs.rsc.org
This study was carried out to evaluate the effects of probiotics administration on the
metabolic and genetic profiles in patients with diabetic nephropathy (DN). This was a …

Ameliorative effect of berberine on neonatally induced type 2 diabetic neuropathy via modulation of BDNF, IGF-1, PPAR-γ, and AMPK expressions

G Zhou, M Yan, G Guo, N Tong - Dose-Response, 2019 - journals.sagepub.com
Neonatal-streptozotocin (n-STZ)-induced diabetes mimics most of the clinicopathological
symptoms of type 2 diabetes mellitus (T2DM) peripheral neuropathy. Berberine, a plant …

A differential diagnosis model for diabetic nephropathy and non-diabetic renal disease in patients with type 2 diabetes complicated with chronic kidney disease

Z Yang, L Feng, Y Huang, N Xia - Diabetes, metabolic syndrome …, 2019 - Taylor & Francis
Purpose Differentiating between diabetic nephropathy (DN) and non-diabetic renal disease
(NDRD) is difficult and inefficient. The aim of the present study was to create a model for the …

Intestinal microbiome diversity of diabetic and non-diabetic kidney disease: Current status and future perspective

S Das, R Gnanasambandan - Life Sciences, 2023 - Elsevier
A significant portion of the health burden of diabetic kidney disease (DKD) is caused by both
type 1 and type 2 diabetes which leads to morbidity and mortality globally. It is one of the …

Urinary chemokine CXC motif ligand 16 and endostatin as predictors of tubulointerstitial fibrosis in patients with advanced diabetic kidney disease

YH Lee, KP Kim, SH Park, DJ Kim… - Nephrology Dialysis …, 2021 - academic.oup.com
Background Interstitial fibrosis and tubular atrophy (IFTA) is a well-recognized risk factor for
poor renal outcome in patients with diabetic kidney disease (DKD). However, a noninvasive …