The development of surfaces that have switchable properties, also known as smart surfaces,
have been actively pursued in the past few years. The recent surge of interest in these …

Innovative technical solutions to realize optical biosensors with improved performance are
continuously proposed. Progress in material fabrication enables developing novel …

The desire to improve and decentralize diagnostic platforms to facilitate highly precise and
personalized medicine has motivated the development of a large number of electrochemical …

The ultimate goal of implantable bioanalytical sensors is to enable the continuous and
precise monitoring of clinically and physiologically important targets in the body for …

Solid-state nanopores have emerged as promising platforms for biosensing including
diagnostics for disease detection. Here we show nanopore experiments that detect CRISPR …

Electrochemical, aptamer-based (E-AB) sensors support continuous, real-time
measurements of specific molecular targets in complex fluids such as undiluted serum. They …

Both clinical and analytical metrics produced by microarray-based assay technology have
recognized problems in reproducibility, reliability and analytical sensitivity. These issues are …

This review discusses the application of quantum dots (QDs), gold nanoparticles (NPs), and
molecular switches in optical nucleic-acid diagnostics. The size-dependent optical …

Here we have demonstrated a general, sensitive, and selective approach for the detection of
macromolecules that bind to specific small molecule recognition elements. Our …

The creation of gold surfaces modified by single-or double-stranded DNA self-assembled
monolayers (SAMs) is shown to produce heterogeneous surface packing densities through …