New approaches in the treatment of hypertension

S Oparil, RE Schmieder - Circulation research, 2015 - Am Heart Assoc
Hypertension is the most common modifiable risk factor for cardiovascular disease and
death, and lowering blood pressure with antihypertensive drugs reduces target organ …

[HTML][HTML] SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance

T Leiner, J Bogaert, MG Friedrich, R Mohiaddin… - Journal of …, 2020 - Elsevier
Abstract The Society for Cardiovascular Magnetic Resonance (SCMR) last published its
comprehensive expert panel report of clinical indications for CMR in 2004. This new …

Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open …

M Azizi, M Sapoval, P Gosse, M Monge, G Bobrie… - The Lancet, 2015 - thelancet.com
Background Conflicting blood pressure-lowering effects of catheter-based renal artery
denervation have been reported in patients with resistant hypertension. We compared the …

Evaluation of adherence should become an integral part of assessment of patients with apparently treatment-resistant hypertension

E Berra, M Azizi, A Capron, A Høieggen, F Rabbia… - …, 2016 - Am Heart Assoc
298 Hypertension August 2016 drug adherence. Assessment of adherence is not part of
routine clinical practice and is seldom performed in studies, even those testing drugs or …

Impact of lesion placement on efficacy and safety of catheter-based radiofrequency renal denervation

F Mahfoud, S Tunev, S Ewen, B Cremers… - Journal of the American …, 2015 - jacc.org
Background: Insufficient procedural efficacy has been proposed to explain nonresponse to
renal denervation (RDN). Objectives: The aim of this study was to examine the impact of …

Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the …

J Rosa, P Widimský, P Toušek, O Petrák, K Čurila… - …, 2015 - Am Heart Assoc
This prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-
based renal denervation (Symplicity, Medtronic) versus intensified pharmacological …

First report of the Global SYMPLICITY Registry on the effect of renal artery denervation in patients with uncontrolled hypertension

M Böhm, F Mahfoud, C Ukena, UC Hoppe… - …, 2015 - Am Heart Assoc
This study aimed to assess the safety and effectiveness of renal denervation using the
Symplicity system in real-world patients with uncontrolled hypertension (NCT01534299) …

Reduced blood pressure-lowering effect of catheter-based renal denervation in patients with isolated systolic hypertension: data from SYMPLICITY HTN-3 and the …

F Mahfoud, G Bakris, DL Bhatt, M Esler… - European heart …, 2017 - academic.oup.com
Aims Catheter-based renal artery denervation (RDN) has been shown to lower blood
pressure (BP) in certain patients with uncontrolled hypertension. Isolated systolic …

Catheter-based renal denervation for resistant hypertension: 12-month results of the EnligHTN I first-in-human study using a multielectrode ablation system

V Papademetriou, CP Tsioufis, A Sinhal, DP Chew… - …, 2014 - Am Heart Assoc
Renal denervation has emerged as a novel approach for the treatment of patients with drug-
resistant hypertension. To date, only limited data have been published using multielectrode …

Adjusted drug treatment is superior to renal sympathetic denervation in patients with true treatment-resistant hypertension

FEM Fadl Elmula, P Hoffmann, AC Larstorp… - …, 2014 - Am Heart Assoc
We aimed to investigate for the first time the blood pressure (BP)–lowering effect of renal
sympathetic denervation (RDN) versus clinically adjusted drug treatment in true treatment …