Adiponectin regulation and function

H Fang, RL Judd - Comprehensive Physiology, 2011 - Wiley Online Library
Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review

K Michalakis, G Mintziori, A Kaprara, BC Tarlatzis… - Metabolism, 2013 - Elsevier
The aim of this narrative review is to provide current evidence for the interaction between
obesity, metabolic syndrome (MS) and reproductive axis. Gonadotropin-releasing hormone …

Adiponectin action from head to toe

K Brochu-Gaudreau, C Rehfeldt, R Blouin, V Bordignon… - Endocrine, 2010 - Springer
Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its
involvement in obesity-related disorders such as insulin resistance, type 2 diabetes mellitus …

Remodeling and Fibrosis of the Cardiac Muscle in the Course of Obesity—Pathogenesis and Involvement of the Extracellular Matrix

J Kruszewska, A Cudnoch-Jedrzejewska… - International Journal of …, 2022 - mdpi.com
Obesity is a growing epidemiological problem, as two-thirds of the adult population are
carrying excess weight. It is a risk factor for the development of cardiovascular diseases …

BOARD-INVITED REVIEW: The biology and regulation of preadipocytes and adipocytes in meat animals,

GJ Hausman, MV Dodson, K Ajuwon… - Journal of animal …, 2009 - academic.oup.com
The quality and value of the carcass in domestic meat animals are reflected in its protein and
fat content. Preadipocytes and adipocytes are important in establishing the overall fatness of …

Mechanisms of adiponectin action in fertility: an overview from gametogenesis to gestation in humans and animal models in normal and pathological conditions

A Barbe, A Bongrani, N Mellouk, A Estienne… - International journal of …, 2019 - mdpi.com
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose
tissue and plays a key role in the control of energy metabolism thanks to its insulin …

Adiponectin actions in the cardiovascular system

TA Hopkins, N Ouchi, R Shibata… - Cardiovascular …, 2007 - academic.oup.com
Obesity is strongly associated with the pathogenesis of type 2 diabetes, hypertension, and
cardiovascular disease. Levels of the hormone adiponectin are downregulated in obese …

Adipokines: implications for female fertility and obesity

M Mitchell, DT Armstrong, RL Robker… - …, 2005 - rep.bioscientifica.com
Obesity is associated with a diverse set of metabolic disorders, and has reproductive
consequences that are complex and not well understood. The adipose tissue-produced …

Cardioprotection by adiponectin

N Ouchi, R Shibata, K Walsh - Trends in cardiovascular medicine, 2006 - Elsevier
Obesity-related disorders are closely associated with the pathogenesis of cardiovascular
disease. Adiponectin is a circulating adipose tissue-derived hormone that is down-regulated …

Adipose tissue and reproductive health

H Mathew, VD Castracane, C Mantzoros - Metabolism, 2018 - Elsevier
The understanding of adipose tissue role has evolved from that of a depot energy storage
organ to a dynamic endocrine organ. While genetics, sexual phenotype and sex steroids …