The emergence of bacteria resistance to most of the currently available antibiotics has become a critical therapeutic problem. The bacteria causing both hospital and community …
Currently, the bacterial resistance, especially to most commonly used antibiotics has proved to be a severe therapeutic problem. Nosocomial and community-acquired infections are …
NS El-Safory, AE Fazary, CK Lee - Carbohydrate polymers, 2010 - Elsevier
Given the constant synthesis and degradation of hyaluronan (hyaluronic acid, HA) in tissues, it is remarkable that the human body maintains precise levels of hyaluronan as tightly as it …
M Sindelar, J Jilkova, L Kubala, V Velebny… - Colloids and Surfaces B …, 2021 - Elsevier
Hyaluronan is a non-sulfated negatively-charged linear polymer distributed in most parts of the human body, where it is located around cells in the extracellular matrix of connective …
T Mori, N Masuzawa, K Kondo… - Bioscience …, 2023 - academic.oup.com
Haliscomenobacter hydrossis is a filamentous bacterium common in activated sludge. The bacterium was found to utilize hyaluronic acid, and hyaluronate lyase activity was detected …
JY Jiang, D Xue, JS Gong, QX Zheng, YS Zhang… - Bioresources and …, 2024 - Springer
Hyaluronan (HA), a natural high molecular weight polysaccharide, has extensive applications in cosmetology and medical treatment. Hyaluronan-degrading enzymes (Hyals) …
P Mishra, R Prem Kumar, AS Ethayathulla… - The FEBS …, 2009 - Wiley Online Library
Hyaluronate lyases are a class of endoglycosaminidase enzymes with a high level of complexity and heterogeneity. The main function of the Streptococcus pyogenes …
Streptococcus pyogenes is associated with a wide variety of mucosal and invasive infections that claim human life. The conversion from non pathogenic to toxigenic strain of S. pyogenes …
NS El-Safory, CK Lee - Carbohydrate polymers, 2010 - Elsevier
Hyaluronate lyase cleaves hyaluronan chains at a β-d-GalNAc-(1→ 4)-β-d-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-β-d-gluc-4-enuronosyl)-N-acetyl …