Baculovirus: an insect-derived vector for diverse gene transfer applications

KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin… - Molecular Therapy, 2013 - cell.com
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

Baculovirus as a tool for gene delivery and gene therapy

C Ono, T Okamoto, T Abe, Y Matsuura - Viruses, 2018 - mdpi.com
Based on its ability to express high levels of protein, baculovirus has been widely used for
recombinant protein production in insect cells for more than thirty years with continued …

Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications

CY Chen, CY Lin, GY Chen, YC Hu - Biotechnology advances, 2011 - Elsevier
Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …

A comparative review of viral entry and attachment during large and giant dsDNA virus infections

H Sobhy - Archives of virology, 2017 - Springer
Viruses enter host cells via several mechanisms, including endocytosis, macropinocytosis,
and phagocytosis. They can also fuse at the plasma membrane and can spread within the …

Baculovirus GP64-mediated entry into mammalian cells

C Kataoka, Y Kaname, S Taguwa, T Abe… - Journal of …, 2012 - Am Soc Microbiol
The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) serves as
an efficient viral vector, not only for abundant gene expression in insect cells, but also for …

Rho'ing in and out of cells: viral interactions with Rho GTPase signaling

C Van den Broeke, T Jacob, HW Favoreel - Small GTPases, 2014 - Taylor & Francis
Rho GTPases are key regulators of actin and microtubule dynamics and organization.
Increasing evidence shows that many viruses have evolved diverse interactions with Rho …

Internalization of coxsackievirus A9 is mediated by β2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin

O Heikkilä, P Susi, T Tevaluoto, H Härmä… - Journal of …, 2010 - Am Soc Microbiol
ABSTRACT Coxsackievirus A9 (CAV9) is a member of the human enterovirus B species
within the Enterovirus genus of the family Picornaviridae. It has been shown to utilize αV …

An overview of nanoparticle based delivery for treatment of inner ear disorders

I Pyykkö, J Zou, A Schrott-Fischer, R Glueckert… - Auditory and Vestibular …, 2016 - Springer
Nanoparticles offer new possibilities for inner ear treatment as they can carry a variety of
drugs, protein, and nucleic acids to inner ear. Nanoparticles are equipped with several …

Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens

SY Lin, YC Chung, YC Hu - Expert review of vaccines, 2014 - Taylor & Francis
After three decades of development, the baculovirus/insect cell expression system is now
recognized as a powerful platform for recombinant protein production. With a number of …

6-O- and N-Sulfated Syndecan-1 Promotes Baculovirus Binding and Entry into Mammalian Cells

KE Makkonen, P Turkki, JP Laakkonen… - Journal of …, 2013 - Am Soc Microbiol
Baculoviruses are insect-specific viruses commonly found in nature. They are not able to
replicate in mammalian cells but can transduce them when equipped with an appropriate …