Ferroptosis is a kind of regulated cell death (RCD) caused by the redox state disorder of
intracellular microenvironment controlled by glutathione (GSH) peroxidase 4 (GPX4), which …

Ferroptosis is a recently defined type of regulated cell death caused by an excess iron-
dependent accumulation of lipid peroxides and is morphologically and biochemically distinct …

Age‐related macular degeneration (AMD) is a major cause of visual impairment and severe
vision loss worldwide, while the currently available treatments are often unsatisfactory …

Endothelial cells (ECs) angiogenesis is the process of sprouting new vessels from the
existing ones, playing critical roles in physiological and pathological processes such as …

Abstract The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a
transmembrane heme exporter essential for embryonic vascular development. However, the …

Porphyrin and iron are ubiquitous and essential for sustaining life in virtually all living
organisms. Unlike iron, which exists in many forms, porphyrin macrocycles are mostly …

Choroidal neovascularization (CNV) occurs in neovascular age-related macular
degeneration (AMD) and often leads to permanent visual impairment. Intravitreal injection of …

Rationale: Choroidal neovascularization (CNV) is a major cause of severe vision loss and
occurs in many ocular diseases, especially neovascular age-related macular degeneration …

Neovascular age‐related macular degeneration (nAMD) is a leading cause of vision loss in
older adults. nAMD is treated with biologics targeting vascular endothelial growth factor; …

Wet age-related macular degeneration, which is characterized by choroidal
neovascularization (CNV) and induces obvious vision loss. Vascular endothelial growth …