Dysregulation of neural stem cells (NSCs) is associated with several neurodevelopmental
disorders, including epilepsy and autism spectrum disorder. The mammalian target of …

Mounting evidence indicates that Wnt signaling is relevant to pathophysiology of diverse
mental illnesses including schizophrenia, bipolar disorder, and autism spectrum disorder. In …

Schizophrenia is a complex mental disorder that displays behavioral deficits such as
decreased sensory gating, reduced social interaction and working memory deficits. The …

Amyotrophic lateral sclerosis (ALS) is the most prevalent neuromuscular disease worldwide.
It is a lethal and progressive neurodegenerative disease, principally affecting motor …

During embryogenesis, cortical interneurons are generated by ventral progenitors located in
the ganglionic eminences of the telencephalon. They travel along multiple tangential paths …

Epigenetic mechanisms of gene regulation, including DNA methylation and histone
modifications, call increasing attention in the context of development and human health …

Cell polarity is defined as the asymmetric distribution of cellular components along an axis.
Most cells, from the simplest single-cell organisms to highly specialized mammalian cells …

Helper and cytotoxic T cells accomplish focused secretion through the movement of vesicles
toward the microtubule organizing center (MTOC) and translocation of the MTOC to the …

The 17p13. 3 chromosome region is often deleted or duplicated in humans, resulting in
severe neurodevelopmental disorders such as Miller–Dieker syndrome (MDS) and 17p13. 3 …

ZNF804A (Zinc Finger Protein 804A) has been identified as a candidate gene for
schizophrenia (SZ), autism spectrum disorders (ASD), and bipolar disorder (BD) in …