A large body of evidence suggests the existence of polarized human T cell responses,
reminiscent of Th1 and Th2 subsets described for mouse T cells. Human Th1-like cells …

Differential production of cytokines by helper T (TH) cells during an immune reaction has
important regulatory effects on the nature of the response. Responses in mice that are …

Monocytes and macrophages are important effectors and regulators of inflammation, and
both can be divided into distinct subsets based on their phenotypes. The developmental and …

Evidence is accumulating to suggest the existence of polarized human T-cell responses,
reminiscent of TH 1 and TH 2 subsets described for mouse T cells. Human TH 1 cells …

Recent attention has focused on the T helper type 2 (Th2) lymphocyte as a source of
interleukin 4 (IL-4) in allergic disease. However, Th2 cells themselves require a pulse of IL-4 …

The cellular basis of immunological memory remains a controversial issue. Here we show
that basophils bound large amounts of intact antigens on their surface and were the main …

Basophils are the rarest granulocytes and represent less than 1% of peripheral blood
leukocytes. They are evolutionarily conserved in many animal species, but their functional …

In contrast to most cytokines, interleukin 4 (IL-4) expression is restricted to T lymphocytes,
with the exception of mast cell lines and mast cells, as more recently demonstrated in …

Basophils are the rarest granulocytes which represent< 1% of peripheral blood leukocytes.
Basophils bear several phenotypic similarities to tissue‐resident mast cells and therefore …

Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …