Effect of DMARDs on the immunogenicity of vaccines

Y van Sleen, KSM van der Geest… - Nature Reviews …, 2023 - nature.com
Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

[HTML][HTML] Vaccination in the Era of Immunosuppression

F Alnaimat, JJG Sweis, J Jansz, Z Modi, S Prasad… - Vaccines, 2023 - mdpi.com
Patients with autoimmune inflammatory rheumatic diseases (AIIRDs) are at increased risk
for severe infections. Vaccine responses and safety profiles may differ between AIIRD …

[HTML][HTML] Booster dose of SARS-CoV-2 messenger RNA vaccines strengthens the specific immune response of patients with rheumatoid arthritis: A prospective …

C Farroni, A Aiello, A Picchianti-Diamanti… - International Journal of …, 2022 - Elsevier
Objectives To characterize the kinetics of humoral and T-cell responses in rheumatoid
arthritis (RA)-patients followed up to 4-6 weeks (T3) after the SARS-CoV-2 vaccine booster …

Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive …

SW Syversen, I Jyssum, AT Tveter, J Sexton… - RMD open, 2022 - rmdopen.bmj.com
Objectives Humoral vaccine responses to SARS-CoV-2 vaccines are impaired and short
lasting in patients with immune-mediated inflammatory diseases (IMID) following two …

[HTML][HTML] Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study

KH Bjørlykke, HS Ørbo, AT Tveter, I Jyssum… - The Lancet …, 2023 - thelancet.com
Background Data on response and safety of repeated vaccinations and hybrid immunity in
patients with immune-mediated inflammatory diseases on immunosuppressive therapy is …

[HTML][HTML] Efficacy of COVID-19 mRNA vaccination in patients with autoimmune disorders: humoral and cellular immune response

F Filippini, M Giacomelli, C Bazzani, M Fredi… - BMC medicine, 2023 - Springer
Background The impact of immunosuppressive therapies on the efficacy of vaccines to
SARS-CoV-2 is not completely clarified. We analyzed humoral and T cell-mediated …

Pausing methotrexate prevents impairment of Omicron BA. 1 and BA. 2 neutralisation after COVID-19 booster vaccination

E Habermann, L Gieselmann, P Tober-Lau… - RMD open, 2022 - rmdopen.bmj.com
Objective The level of neutralising capacity against Omicron BA. 1 and BA. 2 after third
COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is …

Safety and immunogenicity of a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases compared with healthy controls

F Kartnig, D Mrak, E Simader, S Tobudic… - Annals of the …, 2023 - ard.bmj.com
Objectives A third COVID-19 vaccination is recommended for immunosuppressed patients.
However, data on immunogenicity and safety of a third COVID-19 vaccination in patients …

[HTML][HTML] The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls …

IE Christensen, I Jyssum, AT Tveter, J Sexton, TT Tran… - BMC medicine, 2022 - Springer
Background The durability of vaccine-induced humoral immunity against SARS-CoV-2 in
patients with immune-mediated inflammatory diseases (IMIDs) on immunosuppressive …

Susceptibility to COVID-19 and immunologic response to vaccination in patients with immune-mediated inflammatory diseases

A Finckh, A Ciurea, CE Raptis… - The Journal of …, 2023 - academic.oup.com
Immune-mediated inflammatory diseases (IMIDs) are a highly heterogeneous group of
diseases that share a common etiology of immune dysregulation, such as rheumatoid …