Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

JMV Makabenta, A Nabawy, CH Li… - Nature Reviews …, 2021 - nature.com
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Combatting antibiotic-resistant bacteria using nanomaterials

A Gupta, S Mumtaz, CH Li, I Hussain… - Chemical Society …, 2019 - pubs.rsc.org
The dramatic increase in antimicrobial resistance for pathogenic bacteria constitutes a key
threat to human health. The Centers for Disease Control and Prevention has recently stated …

Supramolecular Photothermal Cascade Nano‐Reactor Enables Photothermal Effect, Cascade Reaction, and In Situ Hydrogelation for Biofilm‐Associated Tooth …

L Chen, M Peng, J Zhou, X Hu, Y Piao, H Li… - Advanced …, 2023 - Wiley Online Library
Due to the emergence of drug resistance in bacteria and biofilm protection, achieving a
satisfactory therapeutic effect for bacteria‐infected open wounds with conventional …

Bioinspired silver nanoparticle-based nanocomposites for effective control of plant pathogens: A review

DY Kim, SKS Patel, K Rasool, N Lone, SK Bhatia… - Science of the Total …, 2024 - Elsevier
Plant pathogens, including bacteria, fungi, and viruses, pose significant challenges to the
farming community due to their extensive diversity, the rapidly evolving phenomenon of multi …

Guanidinium‐decorated nanostructure for precision sonodynamic‐catalytic therapy of MRSA‐infected osteomyelitis

Y Cheng, Y Zhang, Z Zhao, G Li, J Li, A Li… - Advanced …, 2022 - Wiley Online Library
Osteomyelitis caused by methicillin‐resistant Staphylococcus aureus (MRSA) biofilm
infection is difficult to eradicate and can even be life‐threatening. Given that the infection is …

Antimicrobial hybrid amphiphile via dynamic covalent bonds enables bacterial biofilm dispersal and bacteria eradication

Y Zhan, X Hu, Y Li, Y Wang, H Chen… - Advanced Functional …, 2023 - Wiley Online Library
To tackle the problems caused by bacterial biofilms, herein, this study reports an
antimicrobial hybrid amphiphile (aHA) via dynamic covalent bonds for eradicating …

Size and charge adaptive clustered nanoparticles targeting the biofilm microenvironment for chronic lung infection management

Y Gao, J Wang, M Chai, X Li, Y Deng, Q Jin, J Ji - ACS nano, 2020 - ACS Publications
Chronic lung infection caused by bacterial biofilms is an extremely serious clinical problem,
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …

Polymers as advanced antibacterial and antibiofilm agents for direct and combination therapies

Z Si, W Zheng, D Prananty, J Li, CH Koh, ET Kang… - Chemical …, 2022 - pubs.rsc.org
The growing prevalence of antimicrobial drug resistance in pathogenic bacteria is a critical
threat to global health. Conventional antibiotics still play a crucial role in treating bacterial …

Approaches for the inhibition and elimination of microbial biofilms using macromolecular agents

LD Blackman, Y Qu, P Cass, KES Locock - Chemical Society Reviews, 2021 - pubs.rsc.org
Biofilms are complex three-dimensional structures formed at interfaces by the vast majority
of bacteria and fungi. These robust communities have an important detrimental impact on a …

Self-propelled active photothermal nanoswimmer for deep-layered elimination of biofilm in vivo

T Cui, S Wu, Y Sun, J Ren, X Qu - Nano Letters, 2020 - ACS Publications
Increasing penetration of antibacterial agents into biofilm is a promising strategy for
improvement of therapeutic effect and slowdown of the progression of antibiotic resistance …