Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor

JM Dayer, E Choy - Rheumatology, 2010 - academic.oup.com
RA is a chronic, debilitating disease in which articular inflammation and joint destruction are
accompanied by systemic manifestations including anaemia, fatigue and osteoporosis. IL-6 …

Thymoquinone (TQ) inhibits the replication of intracellular Mycobacterium tuberculosis in macrophages and modulates nitric oxide production

HA Mahmud, H Seo, S Kim, MI Islam, KW Nam… - … and alternative medicine, 2017 - Springer
Background Human tuberculosis, which is caused by the pathogen Mycobacterium
tuberculosis, remains a major public health concern. Increasing drug resistance poses a …

The role of flow cytometry in the interferon‐γ‐based diagnosis of active tuberculosis and its coinfection with HIV‐1—A technically oriented review

G Janossy, SM Barry, RAM Breen… - Cytometry Part B …, 2008 - Wiley Online Library
TB remains uncontrolled. In resource‐rich countries, only∼ 60% of diagnoses are confirmed
by culture. The number is lower in resource‐poor environments. Huge scope therefore exists …

Immunoproteomic Identification of Secretory and Subcellular Protein Antigens and Functional Evaluation of the Secretome Fraction of Mycobacterium immunogenum, a Newly …

MK Gupta, V Subramanian… - Journal of Proteome …, 2009 - ACS Publications
Mycobacterium immunogenum has been associated with occupational pulmonary disease
hypersensitivity pneumonitis (HP). The aim of this study was to identify immunogenic …

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

R Keeton, N Allie, I Dambuza, B Abel… - The Journal of …, 2014 - Am Soc Clin Investig
Development of host protective immunity against Mycobacterium tuberculosis infection is
critically dependent on the inflammatory cytokine TNF. TNF signals through 2 receptors …

Impaired generation of reactive oxygen species during differentiation of dendritic cells (DCs) by Mycobacterium tuberculosis secretory antigen (MTSA) and …

A Sinha, A Singh, V Satchidanandam… - The Journal of …, 2006 - journals.aai.org
We investigated the role of reactive oxygen species (ROS) in dendritic cell (DC)
differentiation by 10-kDa Mycobacterium tuberculosis secretory Ag (MTSA) and survival of …

[HTML][HTML] Suppression of Mycobacterium tuberculosis induced reactive oxygen species (ROS) and TNF-α mRNA expression in human monocytes by allicin

N Hasan, N Yusuf, Z Toossi, N Islam - FEBS letters, 2006 - Elsevier
Chronic inflammation associated with tumor necrosis factor (TNF)-α and reactive oxygen
species (ROS) is the hallmark of tuberculosis. Mycobacterium tuberculosis (MTB) directly …

Allicin-induced suppression of Mycobacterium tuberculosis 85B mRNA in human monocytes

N Hasan, MU Siddiqui, Z Toossi, S Khan, J Iqbal… - Biochemical and …, 2007 - Elsevier
Despite of encountering a robust immune response, Mycobacterium tuberculosis (MTB)
successfully survives and persists in the human host. We investigated the early regulation of …

[HTML][HTML] Bacillus Calmette‑Guérin induces rapid gene expression changes in human bladder cancer cell lines that may modulate its survival

JN Rahmat, K Esuvaranathan… - Oncology …, 2018 - spandidos-publications.com
Abstract Bacillus Calmette‑Guérin (BCG) immunotherapy is the standard therapy for non‑
muscle invasive bladder cancer. The aim of the present study was to identify genes that are …

Induction of Serine Protease Inhibitor 9 by Mycobacterium tuberculosis Inhibits Apoptosis and Promotes Survival of Infected Macrophages

Z Toossi, M Wu, R Rojas, B Kalsdorf… - Journal of Infectious …, 2012 - academic.oup.com
Our recent microarray analysis of infected human alveolar macrophages (AMs) found serine
protease inhibitor 9 (PI-9) to be the most prominently expressed of a cluster of apoptosis …