Trypanosoma cruzi surface mucins: host-dependent coat diversity
CA Buscaglia, VA Campo, ACC Frasch… - Nature Reviews …, 2006 - nature.com
The surface of the protozoan parasite Trypanosoma cruzi is covered in mucins, which
contribute to parasite protection and to the establishment of a persistent infection. Their …
contribute to parasite protection and to the establishment of a persistent infection. Their …
Prevalence and implications of multiple-strain infections
O Balmer, M Tanner - The Lancet infectious diseases, 2011 - thelancet.com
Infections frequently contain multiple strains (genotypes) of the same pathogen, yet they are
still usually treated as uniform entities. In this Review, we discuss problems with inconsistent …
still usually treated as uniform entities. In this Review, we discuss problems with inconsistent …
Timing and sequence of vaccination against COVID-19 and influenza (TACTIC): a single-blind, placebo-controlled randomized clinical trial
Background Novel mRNA-based vaccines have been used to protect against SARS-CoV-2,
especially in vulnerable populations who also receive an annual influenza vaccination. The …
especially in vulnerable populations who also receive an annual influenza vaccination. The …
Type 1 and 2 immunity following vaccination is influenced by nanoparticle size: formulation of a model vaccine for respiratory syncytial virus
PL Mottram, D Leong, B Crimeen-Irwin… - Molecular …, 2007 - ACS Publications
Previous studies compared uptake by dendritic cells (DC) of 20, 40, 100, 200, 500, 1000,
and 2000 nm beads in vivo. When beads were used as antigen carriers, bead size …
and 2000 nm beads in vivo. When beads were used as antigen carriers, bead size …
Design and pre-clinical evaluation of a universal HIV-1 vaccine
S Letourneau, EJ Im, T Mashishi, C Brereton… - PloS one, 2007 - journals.plos.org
Background One of the big roadblocks in development of HIV-1/AIDS vaccines is the
enormous diversity of HIV-1, which could limit the value of any HIV-1 vaccine candidate …
enormous diversity of HIV-1, which could limit the value of any HIV-1 vaccine candidate …
Does malaria suffer from lack of memory?
SS Struik, EM Riley - Immunological reviews, 2004 - Wiley Online Library
It is widely perceived that immunity to malaria is, to an extent, defective and that one
component of this defective immune response is the inability to induce or maintain long‐term …
component of this defective immune response is the inability to induce or maintain long‐term …
Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection
Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T
cell recognition, may, in part, account for the observed differences in human …
cell recognition, may, in part, account for the observed differences in human …
Malaria parasites: the great escape
Parasites of the genus Plasmodium have a complex life cycle. They alternate between their
final mosquito host and their intermediate hosts. The parasite can be either extra-or …
final mosquito host and their intermediate hosts. The parasite can be either extra-or …
CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes
DL Martin, DB Weatherly, SA Laucella… - PLoS …, 2006 - journals.plos.org
CD8+ T cells are crucial for control of a number of medically important protozoan parasites,
including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the …
including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the …
Cell biology and immunology of malaria
JC Hafalla, O Silvie, K Matuschewski - Immunological reviews, 2011 - Wiley Online Library
Malaria is a vector‐borne infectious disease caused by unicellular parasites of the genus
Plasmodium. These obligate intracellular parasites have the unique capacity to infect and …
Plasmodium. These obligate intracellular parasites have the unique capacity to infect and …