Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
Once a Treg, always a Treg?
DV Sawant, DAA Vignali - Immunological reviews, 2014 - Wiley Online Library
Regulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the
dominant control of immunological tolerance and maintenance of immune homeostasis …
dominant control of immunological tolerance and maintenance of immune homeostasis …
MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells
IS Okoye, SM Coomes, VS Pelly, S Czieso… - Immunity, 2014 - cell.com
Summary Foxp3+ T regulatory (Treg) cells prevent inflammatory disease but the mechanistic
basis of suppression is not understood completely. Gene silencing by RNA interference can …
basis of suppression is not understood completely. Gene silencing by RNA interference can …
Treg functional stability and its responsiveness to the microenvironment
Regulatory T cells (Tregs) prevent autoimmunity and tissue damage resulting from
excessive or unnecessary immune activation through their suppressive function. While their …
excessive or unnecessary immune activation through their suppressive function. While their …
Gene expression profiling for the identification and classification of antibody-mediated heart rejection
Background: Antibody-mediated rejection (AMR) contributes to heart allograft loss. However,
an important knowledge gap remains in terms of the pathophysiology of AMR and how …
an important knowledge gap remains in terms of the pathophysiology of AMR and how …
MicroRNAs as non-invasive biomarkers of heart transplant rejection
JP Duong Van Huyen, M Tible, A Gay… - European heart …, 2014 - academic.oup.com
Aim Rejection is one of the major causes of late cardiac allograft failure and at present can
only be diagnosed by invasive endomyocardial biopsies. We sought to determine whether …
only be diagnosed by invasive endomyocardial biopsies. We sought to determine whether …
Adipose derived mesenchymal stem cell exosomes loaded with miR-10a promote the differentiation of Th17 and Treg from naive CD4+ T cell
Aims The balance between various CD4+ T cell subsets through highly regulated
differentiation of naïve T cells is critical to ensure proper immune response, disruption of …
differentiation of naïve T cells is critical to ensure proper immune response, disruption of …
The microbiota and epigenetic regulation of T helper 17/regulatory T cells: in search of a balanced immune system
Immune cells not only affect tissue homeostasis at the site of inflammation but also exert
systemic effects contributing to multiple chronic conditions. Recent evidence clearly supports …
systemic effects contributing to multiple chronic conditions. Recent evidence clearly supports …
The microRNA-183 cluster: the family that plays together stays together
S Dambal, M Shah, B Mihelich, L Nonn - Nucleic acids research, 2015 - academic.oup.com
Abstract The microRNA (miR) 183 cluster, which is comprised of miRs-183,-96 and-182, is
also a miR family with sequence homology. Despite the strong similarity in the sequences of …
also a miR family with sequence homology. Despite the strong similarity in the sequences of …
[HTML][HTML] Donor-derived exosomes with lung self-antigens in human lung allograft rejection
The immunological role of exosomes in allograft rejection remains unknown. We sought to
determine whether exosomes are induced during lung allograft rejection and to define the …
determine whether exosomes are induced during lung allograft rejection and to define the …