What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review

KM Saqr, S Rashad, S Tupin… - Journal of Cerebral …, 2020 - journals.sagepub.com
Despite the plethora of published studies on intracranial aneurysms (IAs) hemodynamic
using computational fluid dynamics (CFD), limited progress has been made towards …

Role of fluid dynamics and inflammation in intracranial aneurysm formation

AS Turjman, F Turjman, ER Edelman - Circulation, 2014 - Am Heart Assoc
374 Circulation January 21, 2014 to vascular aneurysms, we surmise that aneurysm-
protective flows and wall states maintain vascular homeostasis throughout the cerebral tree …

Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties

A Valencia, P Burdiles, M Ignat, J Mura… - … methods in medicine, 2013 - Wiley Online Library
Computational Structural Dynamics (CSD) simulations, Computational Fluid Dynamics
(CFD) simulation, and Fluid Structure Interaction (FSI) simulations were carried out in an …

A theoretical model for fibroblast-controlled growth of saccular cerebral aneurysms

M Kroon, GA Holzapfel - Journal of Theoretical Biology, 2009 - Elsevier
A new theoretical model for the growth of saccular cerebral aneurysms is proposed by
extending the recent constitutive framework of Kroon and Holzapfel [2007a. A model for …

A pilot study on biaxial mechanical, collagen microstructural, and morphological characterizations of a resected human intracranial aneurysm tissue

DW Laurence, H Homburg, F Yan, Q Tang, KM Fung… - Scientific reports, 2021 - nature.com
Intracranial aneurysms (ICAs) are focal dilatations that imply a weakening of the brain artery.
Incidental rupture of an ICA is increasingly responsible for significant mortality and morbidity …

Cerebral aneurysm evolution modeling from microstructural computational models to machine learning: a review

M Nabaei - Computational biology and chemistry, 2022 - Elsevier
Predicting the future behavior of cerebral aneurysms was the target of several studies in
recent years. When an unruptured cerebral aneurysm is diagnosed, the physician has to …

Biology and hemodynamics of aneurysm rupture

CA Chitwood, ED Shih, O Amili… - Neurosurgery …, 2022 - neurosurgery.theclinics.com
What leads to aneurysm rupture versus stabilization is a question that has perplexed
researchers for decades, the answer would unquestionably influence how aneurysms are …

[PDF][PDF] Modeling of human circle of willis with and without aneurisms

D Ivanov, A Dol, O Pavlova… - Acta of Bioengineering …, 2014 - bibliotekanauki.pl
Purpose: This paper includes results of the first stage of research aimed at the development
of recommendations for physicians in order to help them to choose a particular type of …

Flow in simplified and real models of intracranial aneurysms

G Paál, A Ugron, I Szikora, I Bojtár - International journal of heat and fluid …, 2007 - Elsevier
Numerical flow simulations have been performed on simplified artificial intracranial
aneurysm models, as well as on real models obtained from rotational digital subtraction …

Characterizing tissue remodeling and mechanical heterogeneity in cerebral aneurysms

ED Shih, PP Provenzano, CM Witzenburg… - Journal of Vascular …, 2022 - karger.com
Accurately assessing the complex tissue mechanics of cerebral aneurysms (CAs) is critical
for elucidating how CAs grow and whether that growth will lead to rupture. The factors that …