Simple Summary Diagnosing cancer at an early stage increases the chance of performing
effective treatment in many tumour groups. Key approaches include screening patients who …

Rapid advances in technology and data science have the potential to improve the precision
of preventive and therapeutic interventions, and enable the right treatment to be …

Purpose Polygenic risk influences susceptibility to cancer. We assessed whether polygenic
risk scores could be used in conjunction with other predictors of future disease status in cost …

Purpose In this scoping review, we examined the international literature on risk-stratified
bowel screening to develop recommendations for future research, practice and policy …

Background: Cancer screening tests are recommended to prevent cancer-associated
mortality by detecting precancerous and cancerous lesions in early stages. The COVID-19 …

Background A risk-stratified approach to colorectal cancer (CRC) screening could result in a
more acceptable balance of benefits and harms, and be more cost-effective. Aim To …

Introduction Using risk stratification to determine eligibility for cancer screening is likely to
improve the efficiency of screening programmes by targeting resources towards those most …

BACKGROUND Lynch syndrome is an inherited condition which leads to an increased risk
of colorectal, endometrial and ovarian cancer. Risk-reducing surgery is generally …

Screening for colorectal cancer (CRC) and its precursor lesions, advanced adenomas (AA),
has been shown to effectively reduce CRC-related mortality. However, the method of CRC …

Colorectal cancer (CRC) incidence and mortality is higher in socioeconomically deprived
groups for a variety of reasons, but is exacerbated by poorer screening uptake. However …