Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Capsaicin: A two-decade systematic review of global research output and recent advances against human cancer

TL Adetunji, F Olawale, C Olisah, AE Adetunji… - Frontiers in …, 2022 - frontiersin.org
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is one of the most important natural products
in the genus Capsicum. Due to its numerous biological effects, there has been extensive …

Intestinal-targeted nanotubes-in-microgels composite carriers for capsaicin delivery and their effect for alleviation of Salmonella induced enteritis

Y Yuan, Y Liu, Y He, B Zhang, L Zhao, S Tian, Q Wang… - Biomaterials, 2022 - Elsevier
Salmonella is a word-wide food-borne pathogen, which can cause severe enteritis and
intestinal microbiota imbalance. Capsaicin (Cap), a food-based bioactive ingredient, has …

Formulating co-loaded nanoliposomes with gallic acid and quercetin for enhanced cancer therapy

A Al-Samydai, M Al Qaraleh, KM Al Azzam, A Mayyas… - Heliyon, 2023 - cell.com
Cancer is considered one of the top global causes of death. Natural products have been
used in oncology medicine either in crude form or by utilizing isolated secondary …

Development of pegylated nano‐phytosome formulation with oleuropein and rutin to compare anti‐colonic cancer activity with Olea europaea leaves extract

TH Mahmood, A Al‐Samydai, MA Sulaibi… - Chemistry & …, 2023 - Wiley Online Library
Olive leaf extract is a valuable source of phenolic compounds; primarily, oleuropein (major
component) and rutin. This natural olive leaf extract has potential use as a therapeutic agent …

Capsaicin-incorporated zein electrospun nanofibers: Characterization and release behavior

A Rezazadeh, EM Kia, H Hamishehkar, BKG Jahani… - Food Bioscience, 2022 - Elsevier
Capsaicin is an active compound in hot chili pepper that possesses many beneficial
biological properties. However, sensorial attributes and sensitivity to environmental and food …

Preparation, characterization, wound healing, and cytotoxicity assay of PEGylated nanophytosomes loaded with 6-gingerol

A Al-Samydai, MA Qaraleh, W Alshaer, LK Al-Halaseh… - Nutrients, 2022 - mdpi.com
Background: Nutrients are widely used for treating illnesses in traditional medicine. Ginger
has long been used in folk medicine to treat motion sickness and other minor health …

Anti-cancer activity of sustained release capsaicin formulations

JC Merritt, SD Richbart, EG Moles, AJ Cox… - Pharmacology & …, 2022 - Elsevier
Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic
vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several …

Preparation, characterization, and anticancer activity of pegylated nano liposomal loaded with rutin against human carcinoma cells (HT‐29)

NM Al‐Ekaid, A Al‐Samydai, I Al‐deeb… - Chemistry & …, 2023 - Wiley Online Library
The abstract discusses the development of rutin‐loaded nanoliposomes and their anti‐
colorectal cancer activity against human carcinoma cells (HT‐29). The study characterizes …

[HTML][HTML] Capsaicin Exerts Antitumor Activity in Mesothelioma Cells

E Andretta, A Costa, E Ventura, M Quintiliani… - Nutrients, 2024 - mdpi.com
Background/Objectives: Mesothelioma is an aggressive cancer with limited treatment
options. Mesothelioma therapy often involves a multimodal approach including surgery …