Oncolytic virotherapy: basic principles, recent advances and future directions

D Lin, Y Shen, T Liang - Signal transduction and targeted therapy, 2023 - nature.com
Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

Engineering strategies to enhance oncolytic viruses in cancer immunotherapy

Y Tian, D Xie, L Yang - Signal transduction and targeted therapy, 2022 - nature.com
Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for
patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells …

Oncolytic T-VEC virotherapy plus neoadjuvant chemotherapy in nonmetastatic triple-negative breast cancer: a phase 2 trial

H Soliman, D Hogue, H Han, B Mooney, R Costa… - Nature Medicine, 2023 - nature.com
Talimogene laherparepvec (T-VEC) is an oncolytic virus hypothesized to enhance triple-
negative breast cancer (TNBC) responses to neoadjuvant chemotherapy (NAC). This article …

HMGB1 in the interplay between autophagy and apoptosis in cancer

R Chen, J Zou, X Zhong, J Li, R Kang, D Tang - Cancer Letters, 2024 - Elsevier
Lysosome-mediated autophagy and caspase-dependent apoptosis are dynamic processes
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …

The current landscape of NKT cell immunotherapy and the hills ahead

A Nelson, JD Lukacs, B Johnston - Cancers, 2021 - mdpi.com
Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …

Tumor‐targeted nano‐adjuvants to synergize photomediated immunotherapy enhanced antitumor immunity

H Zhu, C Yang, A Yan, W Qiang, R Ruan, K Ma… - View, 2023 - Wiley Online Library
Photomediated immunotherapy explored to combine the anti‐cancer effect of phototherapy
with the immune enhancement ability of immunotherapy, and shown great prospects for …

[HTML][HTML] Targeting HMGB1: an available therapeutic strategy for breast cancer therapy

H Dong, L Zhang, S Liu - International journal of biological …, 2022 - ncbi.nlm.nih.gov
HMGB1 is a member of highly conserved high mobility group protein superfamily with
intracellular and extracellular distribution. Abnormal HMGB1 levels are frequently …

The redox protein high-mobility group box 1 in cell death and cancer

R Chen, J Zou, R Kang, D Tang - Antioxidants & redox signaling, 2023 - liebertpub.com
Significance: As a redox-sensitive protein, high-mobility group box 1 (HMGB1) is implicated
in regulating stress responses to oxidative damage and cell death, which are closely related …

CAR-NKT cell therapy: a new promising paradigm of cancer immunotherapy

K Hadiloo, S Tahmasebi, A Esmaeilzadeh - Cancer Cell International, 2023 - Springer
Today, cancer treatment is one of the fundamental problems facing clinicians and
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …

Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response

YY Wu, TK Sun, MS Chen, M Munir… - Frontiers in Cellular and …, 2023 - frontiersin.org
Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer
therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis …