The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle
cause it to continuously produce moderate levels of oxidant species, such as reactive …

Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Reactive oxygen species (ROS), products of oxidative stress, contribute to the initiation and
progression of the pathogenesis of various diseases. Glutathione is a major antioxidant that …

The prevalence of cardiovascular disease, oxidative stress-related complications, and
chronic age-related illnesses is gradually increasing worldwide. Several causes include the …

Age-related loss of skeletal muscle mass and function, termed sarcopenia, could impair the
quality of life in the elderly. The mechanisms involved in skeletal muscle aging are intricate …

Facioscapulohumeral muscular dystrophy (FSHD) is characterised by descending skeletal
muscle weakness and wasting. FSHD is caused by mis-expression of the transcription factor …

This study investigated the effects of resveratrol and miR-22-3p on muscle fiber type
conversion in mouse C2C12 myotubes. Here we showed that resveratrol significantly …

Sarcopenia is an aging-related skeletal disease characterized by decreased muscle mass,
strength, and physical function, severely affecting the quality of life (QoL) of the elderly …

Glioblastoma multiforme is one of the most deadly malignant tumors, with more than 10,000
cases recorded annually in the United States. Various clinical analyses and studies show …

Reduction in muscle strength with aging is due to both loss of muscle mass (quantity) and
intrinsic force production (quality). Along with decreased functional capacity of the muscle …