Immunomodulatory potential of fungal extracellular vesicles: Insights for therapeutic applications

S Nenciarini, D Cavalieri - Biomolecules, 2023 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicular organelles that perform a variety of
biological functions including cell communication across different biological kingdoms. EVs …

The paradoxical and still obscure properties of fungal extracellular vesicles

AC Piffer, D Kuczera, ML Rodrigues, L Nimrichter - Molecular Immunology, 2021 - Elsevier
Early compositional studies of fungal EVs revealed a complex combination of biomolecules,
including proteins, lipids, glycans, polysaccharides, nucleic acid and pigments, indicating …

Comparative molecular and immunoregulatory analysis of extracellular vesicles from Candida albicans and Candida auris

D Zamith-Miranda, HM Heyman, SP Couvillion… - Msystems, 2021 - Am Soc Microbiol
Candida auris is a recently described multidrug-resistant pathogenic fungus that is
increasingly responsible for health care-associated outbreaks across the world …

Characterization of extracellular vesicles produced by Aspergillus fumigatus protoplasts

J Rizzo, T Chaze, K Miranda, RW Roberson… - MSphere, 2020 - Am Soc Microbiol
Extracellular vesicles (EVs) are membranous compartments produced by yeast and mycelial
forms of several fungal species. One of the difficulties in perceiving the role of EVs during the …

Fungal extracellular vesicles are involved in intraspecies intracellular communication

TA Bitencourt, O Hatanaka, AM Pessoni, MS Freitas… - MBio, 2022 - Am Soc Microbiol
Fungal infections are associated with high mortality rates in humans. The risk of fungal
diseases creates the urgent need to broaden the knowledge base regarding their …

Ergot Alkaloids Contribute to the Pathogenic Potential of the Fungus Aspergillus leporis

AM Jones, DG Panaccione - Applied and Environmental …, 2023 - Am Soc Microbiol
Opportunistically pathogenic fungi have varying potential to cause disease in animals.
Factors contributing to their virulence include specialized metabolites, which in some cases …

Aspergillus fumigatus G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production …

APC Filho, GTP Brancini, PA de Castro, C Valero… - Mbio, 2020 - Am Soc Microbiol
ABSTRACT G-protein coupled receptors (GPCRs) are extracellular signaling receptors that
sense environmental cues. Fungi sense their environment primarily through GPCR …

Extracellular vesicles from Pneumocystis carinii-infected rats impair fungal viability but are dispensable for macrophage functions

SG Sayson, A Ashbaugh, MT Cushion - Microbiology Spectrum, 2024 - Am Soc Microbiol
Pneumocystis spp. are host obligate fungal pathogens that can cause severe pneumonia in
mammals and rely heavily on their host for essential nutrients. The lack of a sustainable in …

Filamentous fungi extracellular vesicles

T Gonçalves, J Oliveira, C Fernandes - Fungal Extracellular Vesicles …, 2021 - Springer
Since the first description of extracellular vesicles in a filamentous fungus, Alternaria
infectoria, data has been gathered showing the importance of EVs in the interaction of …

Identificação de metabólitos secundários presentes em vesículas extracelulares de Candida albicans durante estresse oxidativo

GES Trentin - 2022 - teses.usp.br
Candida albicans é um fungo comensal em humanos saudáveis, podendo causar infecção
em alguns indivíduos por meio da secreção de diversos fatores de virulência. O sucesso do …