Elucidating the Role of Lipid-Metabolism-Related Signal Transduction and Inhibitors in Skin Cancer
E Kook, DH Kim - Metabolites, 2024 - mdpi.com
Lipids, as multifunctional molecules, play a crucial role in a variety of cellular processes.
These include regulating membrane glycoprotein functions, controlling membrane …
These include regulating membrane glycoprotein functions, controlling membrane …
Inflammasome activation in melanoma progression: the latest update concerning pathological role and therapeutic value
N Pluetrattanabha, T Direksunthorn, I Ahmad… - Archives of …, 2025 - Springer
The progression of melanoma is a complex process influenced by both internal and external
cues which encourage the transition of tumour cells, uncontrolled growth, migration, and …
cues which encourage the transition of tumour cells, uncontrolled growth, migration, and …
PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
Overexpression of phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in
the serine synthesis pathway, promotes melanomagenesis, melanoma cell proliferation, and …
the serine synthesis pathway, promotes melanomagenesis, melanoma cell proliferation, and …
CORO1C Regulates the Malignant Biological Behavior of Ovarian Cancer Cells and Modulates the mRNA Expression Profile through the PI3K/AKT Signaling Pathway
N Lu, Y Guo, L Ren, H Zhao, L Yan, H Han… - Cell Biochemistry and …, 2024 - Springer
Ovarian cancer (OC) is a frequently occurring gynecological tumor, and its global incidence
has recently increased. Coronin-like actin-binding protein 1C (CORO1C) is known to …
has recently increased. Coronin-like actin-binding protein 1C (CORO1C) is known to …
[HTML][HTML] MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability
Overexpression of PHGDH, the rate-limiting enzyme in the serine synthesis pathway,
promotes melanomagenesis, melanoma cell proliferation, and survival of metastases in …
promotes melanomagenesis, melanoma cell proliferation, and survival of metastases in …
[HTML][HTML] A Paradoxical AKT: Exploring the Promise and Challenges of PI3K/AKT/mTOR Targeted Therapies
GL Parkman, SL Holmen - Journal of cancer immunology, 2024 - pmc.ncbi.nlm.nih.gov
A Paradoxical AKT: Exploring the Promise and Challenges of PI3K/AKT/mTOR Targeted
Therapies - PMC Skip to main content Here's how you know Official websites use .gov A .gov …
Therapies - PMC Skip to main content Here's how you know Official websites use .gov A .gov …
Phosphoglycerate Dehydrogenase Regulated by the Mitogen-Activated Protein Kinase Pathway is an Actionable Vulnerability in Cutaneous Melanoma
N Jasani - 2024 - search.proquest.com
Metabolic alterations play a critical role in shaping tumor growth and development. Many
metabolic enzymes are shown to play an important role in different aspects of tumor …
metabolic enzymes are shown to play an important role in different aspects of tumor …