Heterogeneity in protein folding and unfolding reactions

S Bhatia, JB Udgaonkar - Chemical Reviews, 2022 - ACS Publications
Proteins have dynamic structures that undergo chain motions on time scales spanning from
picoseconds to seconds. Resolving the resultant conformational heterogeneity is essential …

Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

Crowding in cellular environments at an atomistic level from computer simulations

M Feig, I Yu, P Wang, G Nawrocki… - The Journal of Physical …, 2017 - ACS Publications
The effects of crowding in biological environments on biomolecular structure, dynamics, and
function remain not well understood. Computer simulations of atomistic models of …

Dynamics of proteins in solution

M Grimaldo, F Roosen-Runge, F Zhang… - Quarterly Reviews of …, 2019 - cambridge.org
The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …

High-resolution neutron spectroscopy using backscattering and neutron spin-echo spectrometers in soft and hard condensed matter

JS Gardner, G Ehlers, A Faraone… - Nature Reviews …, 2020 - nature.com
The instruments best suited to performing high-energy-resolution neutron spectroscopy are
spin-echo spectrometers and backscattering spectrometers. The development of these …

Neutron scattering in the biological sciences: progress and prospects

R Ashkar, H Bilheux, H Bordallo, R Briber… - … Section D: Structural …, 2018 - journals.iucr.org
The scattering of neutrons can be used to provide information on the structure and dynamics
of biological systems on multiple length and time scales. Pursuant to a National Science …

Protein short-time diffusion in a naturally crowded environment

M Grimaldo, H Lopez, C Beck… - The journal of …, 2019 - ACS Publications
The interior of living cells is a dense and polydisperse suspension of macromolecules. Such
a complex system challenges an understanding in terms of colloidal suspensions. As a …

[HTML][HTML] CHESS: The future direct geometry spectrometer at the second target station

G Sala, M Mourigal, C Boone, NP Butch… - Review of Scientific …, 2022 - pubs.aip.org
CHESS, chopper spectrometer examining small samples, is a planned direct geometry
neutron chopper spectrometer designed to detect and analyze weak signals intrinsic to …

Quantum biotechnology

NP Mauranyapin, A Terrasson… - Advanced Quantum …, 2022 - Wiley Online Library
Quantum technologies leverage the laws of quantum physics to achieve performance
advantages in applications ranging from computing to communications and sensing. They …

Short-time transport properties of bidisperse suspensions of immunoglobulins and serum albumins consistent with a colloid physics picture

C Beck, M Grimaldo, H Lopez, S Da Vela… - The Journal of …, 2022 - ACS Publications
The crowded environment of biological systems such as the interior of living cells is
occupied by macromolecules with a broad size distribution. This situation of polydispersity …