Increasing evidence suggests that renal inflammation contributes to the pathogenesis and
progression of diabetic kidney disease (DKD) and that anti-inflammatory therapies might …

The innate immune system includes several classes of pattern recognition receptors (PRRs),
including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding …

Efficient therapies for diabetic kidney disease (DKD), now the leading cause of kidney
failure, are lacking. One hallmark of DKD is sterile inflammation (inflammation in absence of …

Chronic diabetes is associated with metabolic and haemodynamic stresses which can
facilitate modifications to DNA, proteins and lipids, induce cellular dysfunction and damage …

Pyroptosis is one special type of lytic programmed cell death, featured in cell swelling,
rupture, secretion of cell contents and remarkable proinflammation effect. In the process of …

Diabetic nephropathy (DN) as the primary cause of end-stage kidney disease is a common
complication of diabetes. Recent researches have shown the activation of nuclear factor …

S-adenosylhomocysteine (SAH) is hydrolyzed by SAH hydrolase (SAHH) to homocysteine
and adenosine. Increased plasma SAH levels were associated with disturbed renal function …

Significant efforts are being dedicated toward the development of high efficiency, low-cost
lead-free perovskite solar cells (PSCs). In this regard, the lead-free CH 3 NH 3 SnI 3 is …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide.
Exosomes (Exo) derived from human umbilical cord mesenchymal stem cells (HUC-MSCs) …

Chronic renal and vascular oxidative stress in association with an enhanced inflammatory
burden are determinant processes in the development and progression of diabetic …