Vertical transmission of hepatitis B virus: challenges and solutions

I Gentile, G Borgia - International journal of women's health, 2014 - Taylor & Francis
More than 240 million people worldwide are chronically infected with hepatitis B virus (HBV).
Mother-to-child transmission remains the most important mechanism of infection in countries …

Dasabuvir: a non-nucleoside inhibitor of NS5B for the treatment of hepatitis C virus infection

I Gentile, AR Buonomo, G Borgia - Reviews on recent clinical …, 2014 - ingentaconnect.com
Hepatitis C virus (HCV) chronically infects about 2% of the world's population. Approximately
a quarter of these patients will develop, during their life, liver cirrhosis, which entails a high …

Long term persistence of NS5A inhibitor‐resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy

S Yoshimi, M Imamura, E Murakami… - Journal of medical …, 2015 - Wiley Online Library
Although interferon‐free antiviral treatment is expected to improve treatment of hepatitis C, it
is unclear to what extent pre‐existing drug‐resistant amino acid substitutions influence …

Validated stability-indicating HPLC-DAD method for determination of the recently approved hepatitis C antiviral agent daclatasvir

MM Baker, DS El-Kafrawy, MS Mahrous… - annales pharmaceutiques …, 2017 - Elsevier
A comprehensive stability indicating HPLC with diode array detection method was
developed for the determination of the recently approved antiviral drug daclatasvir …

Impact of HCV genotype on treatment regimens and drug resistance: a snapshot in time

L Cuypers, F Ceccherini‐Silberstein… - Reviews in Medical …, 2016 - Wiley Online Library
The introduction of highly potent direct‐acting antivirals (DAAs) has revolutionized hepatitis
C virus treatment. Nevertheless, viral eradication worldwide remains a challenge also in the …

Ledipasvir: a novel synthetic antiviral for the treatment of HCV infection

I Gentile, AR Buonomo, F Borgia… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: About 150,000,000 people worldwide are chronically infected with hepatitis C
virus (HCV). HCV infection can lead to liver cirrhosis, hepatocellular carcinoma and death …

[HTML][HTML] Emerging therapies for hepatitis C

SH Ahn, KH Han - Gut and liver, 2014 - ncbi.nlm.nih.gov
The combination of pegylated interferon (PEG-IFN) and ribavirin (RBV), the current therapy
for hepatitis C virus (HCV) infection, has saved the lives of many HCV-infected patients …

Virocidal activity of Egyptian scorpion venoms against hepatitis C virus

AMH El-Bitar, MMH Sarhan, C Aoki, Y Takahara… - Virology journal, 2015 - Springer
Abstract Background Hepatitis C virus (HCV) is a major global health problem, causing
chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Development of well …

Prevention of mother-to-child transmission of hepatitis B virus and hepatitis C virus

I Gentile, E Zappulo, AR Buonomo… - Expert review of anti …, 2014 - Taylor & Francis
About 240 million people worldwide are chronically infected with hepatitis B virus (HBV).
Vertical transmission is the most important mechanism of infection persistence in endemic …

Antiviral drugs prolong survival in murine recessive dystrophic epidermolysis bullosa

G Tartaglia, I Fuentes, N Patel, A Varughese… - EMBO Molecular …, 2024 - embopress.org
Recessive dystrophic epidermolysis bullosa (RDEB) is a rare inherited skin disease
characterized by defects in type VII collagen leading to a range of fibrotic pathologies …