Cytoplasmic nucleoporin assemblage: the cellular artwork in physiology and disease

J Lin, I Sumara - Nucleus, 2024 - Taylor & Francis
Nucleoporins, essential proteins building the nuclear pore, are pivotal for ensuring
nucleocytoplasmic transport. While traditionally confined to the nuclear envelope, emerging …

How to wrinkle a cell: Emerging mechanisms of microridge morphogenesis

TQ Lu, AP van Loon, A Sagasti - Current Opinion in Cell Biology, 2022 - Elsevier
Microridges are laterally elongated actin-based protrusions arranged in striking maze-like
patterns on the apical surfaces of mucosal epithelial cells. Recent studies have begun to …

Knock-in tagging in zebrafish facilitated by insertion into non-coding regions

DS Levic, N Yamaguchi, S Wang, H Knaut… - …, 2021 - journals.biologists.com
Zebrafish provide an excellent model for in vivo cell biology studies because of their
amenability to live imaging. Protein visualization in zebrafish has traditionally relied on …

Stochastic contraction of myosin minifilaments drives evolution of microridge protrusion patterns in epithelial cells

AP van Loon, IS Erofeev, AB Goryachev… - Molecular Biology of …, 2021 - Am Soc Cell Biol
Actin-based protrusions vary in morphology, stability, and arrangement on cell surfaces.
Microridges are laterally elongated protrusions on mucosal epithelial cells, where they form …

SUMOylation modulates the function of DDX19 in mRNA export

P Banerjee, S Markande, M Kalarikkal… - Journal of Cell …, 2022 - journals.biologists.com
Nuclear export of mRNAs is a critical regulatory step in eukaryotic gene expression. The
mRNA transcript undergoes extensive processing, and is loaded with a set of RNA-binding …

A deep learning framework for quantitative analysis of actin microridges

R Bhavna, M Sonawane - NPJ Systems Biology and Applications, 2023 - nature.com
Microridges are evolutionarily conserved actin-rich protrusions present on the apical surface
of squamous epithelial cells. In zebrafish epidermal cells, microridges form self-evolving …

[HTML][HTML] A Highlights from MBoC Selection: Stochastic contraction of myosin minifilaments drives evolution of microridge protrusion patterns in epithelial cells

AP van Loon, IS Erofeev, AB Goryachev… - Molecular Biology of …, 2021 - ncbi.nlm.nih.gov
Actin-based protrusions vary in morphology, stability, and arrangement on cell surfaces.
Microridges are laterally elongated protrusions on mucosal epithelial cells, where they form …

Stochastic contraction of myosin minifilaments drives evolution of microridge protrusion

AP van Loon, IS Erofeev, AB Goryachev, A Sagasti - Science - Am Soc Cell Biol
Actin-based protrusions vary in morphology, stability, and arrangement on cell surfaces.
Microridges are laterally-elongated protrusions on mucosal epithelial cells, where they form …

Cortical myosin minifilaments orchestrate the arrangement of microridge protrusions on epithelial cell surfaces

AP van Loon, IS Erofeev, AB Goryachev, A Sagasti - bioRxiv, 2020 - biorxiv.org
Actin-based protrusions vary in morphology, stability, and arrangement on cell surfaces.
Microridges are laterally-elongated protrusions arranged in maze-like patterns on mucosal …

Nucleoporin mRNA localization and Annulate Lamellae biosynthesis during Drosophila melanogaster oogenesis

A Schwarz - 2020 - archiv.ub.uni-heidelberg.de
Nuclear pore complexes (NPCs) are large protein assemblies that connect the eukaryotic
nucleus with the cytoplasm, thus facilitating all transport between them. Besides the nuclear …