The Drosophila heart, also referred to as the dorsal vessel, pumps the insect blood, the
hemolymph. The bilateral heart primordia develop from the most dorsally located …

Although the insect circulatory system is involved in a multitude of vital physiological
processes, it has gone grossly understudied. This review highlights this critical physiological …

The circulatory system of Drosophila melanogaster represents an easily amenable genetic
model whose analysis at different levels, ie, from single molecules up to functional anatomy …

The functionality of the Drosophila heart or dorsal vessel is achieved by contributions from
several tissues. The heart tube itself is composed of different types of cardiomyocytes that …

The fruit fly, Drosophila melanogaster, has been used to study genetics, development, and
signaling for nearly a century, but only over the past few decades has this tremendous …

Background: Diabetes mellitus is associated with an increased risk of death and
hospitalisation in patients with chronic heart failure. Better understanding of potential …

In striated muscle tropomyosin (Tm) extends along the length of F-actin-containing thin
filaments. Its location governs access of myosin binding sites on actin and, hence, force …

Striated muscle contraction is regulated by the movement of tropomyosin over the thin
filament surface, which blocks or exposes myosin binding sites on actin. Findings suggest …

Only few examples of transdifferentiation, which denotes the conversion of one differentiated
cell type to another [1], are known to occur during normal development, and more often, it is …

Striated muscle contraction is regulated by the translocation of troponin-tropomyosin strands
over the thin filament surface. Relaxation relies partly on highly-favorable, conformation …