Melasma is a common acquired disorder of pigmentation that negatively impacts quality of
life. Present treatments show poor therapeutic effect with frequent recurrence. This in large …

Psoriasis is a chronic and immune-mediated skin condition characterized by pro-
inflammatory cytokines and keratinocyte hyperproliferation. Dendritic cells, T lymphocytes …

Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general
population. It is a great medical, social and economic burden since PSO is associated with …

Coronavirus disease 2019 (COVID-19) is a viral infection caused by SARS-CoV-2 that
induces a generalized inflammatory state. Organokines (adipokines, osteokines, myokines …

Hidradenitis suppurativa (HS) is an inflammatory skin condition clinically characterized by
recurrent painful deep-seated nodules, abscesses, and sinus tracks in areas bearing …

Mammalian tissue repair forms a scar that fills the injured area with a fibrotic lesion, limiting
tissue function. Adipocytes, lipid-filled cells, well-known for energy storage and endocrine …

Abstract Introduction BCC (Basal Cell Carcinoma) and trichoblastoma are skin tumors
originating from the hair follicle. BCC is the most common non-melanoma skin cancer …

Pruritus or itch generated in the skin is one of the most widespread symptoms associated
with various dermatological and systemic (immunological) conditions. Although many details …

The skin contributes critically to health via its role as a barrier tissue against a multitude of
external pathogens. The barrier function of the skin largely depends on the uppermost …

Wound healing of deep burn injuries is often accompanied by severe scarring, such as
hypertrophic scar (HTS) formation. In severe burn wounds, where the subcutis is also …