Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

Glucocorticoids (GCs) represent a well-known class of lipophilic steroid hormones
biosynthesised, with a circadian rhythm, by the adrenal glands in humans and by the inter …

Abstract Objectives Glucocorticoids (GCs) are one of the most widely prescribed anti-
inflammatory drugs. By acting through their cognate receptor, the glucocorticoid receptor …

The rapid transcriptional response to the transcription factor, glucocorticoid receptor (GR),
including gene activation or repression, is mediated by the spatial association of genes with …

Glucocorticoid-induced (GC) and hypoxia-induced transcriptional responses play an
important role in tissue homeostasis and in the regulation of cellular responses to stress and …

Simple Summary Metastasis is the most dangerous feature of advanced cancers. In vitro
models of this process could help us to study and understand mechanisms that are not …

Here, we investigate the impact of hypoxia on the hepatic response of glucocorticoid
receptor (GR) to dexamethasone (DEX) in mice via RNA‐sequencing. Hypoxia causes three …

Introduction Polymicrobial sepsis causes acute anorexia (loss of appetite), leading to
lipolysis in white adipose tissue and proteolysis in muscle, and thus release of free fatty …

Aberrant carotid body chemoreceptor (CBC) function contributes to increased sympathetic
nerve activity (SNA) and reduced renal blood flow (RBF) in chronic heart failure (CHF) …

Submandibular glands (SMGs) are one of the primary components of salivary glands in
goats. The proteins and biologically active substances secreted by the SMGs change with …