Basal ganglia calcifications could be incidental findings up to 20% of asymptomatic patients
undergoing CT or MRI scan. The presence of neuropsychiatric symptoms associated with …

Primary familial brain calcification (PFBC), also known as Fahr's disease, is a rare inherited
disorder characterized by bilateral calcification in the basal ganglia according to …

Despite the importance of the cerebrovasculature in maintaining normal brain physiology
and in understanding neurodegeneration and drug delivery to the central nervous system …

Microglia are strongly implicated in the development and progression of Alzheimer's disease
(AD), yet their impact on pathology and lifespan remains unclear. Here we utilize a CSF1R …

This systematic MDSGene review covers individuals with confirmed genetic forms of primary
familial brain calcification (PFBC) available in the literature. Data on 516 (47% men) …

ABSTRACT Background Genetic stratification of Parkinson's disease (PD) patients facilitates
gene‐tailored research studies and clinical trials. The objective of this study was to describe …

Introduction There are now a number genes, known to be associated with familial primary
brain calcification (PFBC), causing the so called 'Fahr's' disease or syndrome. These are …

There are several hundred single‐gene disorders that we classify as inborn errors of
metabolism. Inborn errors of metabolism are often rare and highly heterogeneous …

Primary familial brain calcification (PFBC) is an inherited neurodegenerative disorder mainly
characterized by progressive calcium deposition bilaterally in the brain, accompanied by …

Primary familial brain calcification (PFBC) is a rare cerebral microvascular calcifying
disorder with a wide spectrum of motor, cognitive, and neuropsychiatric symptoms. It is …