Misfolded and mistargeted proteins in the early secretory pathway present significant risks to
the cell. A diverse and integrated network of quality control pathways protects the cell from …

The fungal plasma membrane proton pump Pma1 is an integral plasma membrane protein
of the P-type ATPase family. It is an essential enzyme responsible for maintaining a constant …

Ceramides are essential precursors of complex sphingolipids and act as potent signaling
molecules. Ceramides are synthesized in the endoplasmic reticulum (ER) and receive their …

Abstract Endoplasmic reticulum (ER)‐to‐Golgi trafficking is an essential and highly
conserved cellular process. The coat protein complex‐II (COPII) arm of the trafficking …

Cellular regulation of pH is crucial for internal biological processes and for the import and
export of ions and nutrients. In the yeast Saccharomyces cerevisiae, the major proton pump …

Simple Summary Glucose is the preferred carbon source for most cells. Yeast Snf1 (AMPK in
mammals) is the main regulator of the response to low glucose availability. In the last years …

Nutrient transporters have been shown to translocate to the plasma membrane (PM) of the
filamentous fungus Aspergillus nidulans via an unconventional trafficking route that …

The highly conserved endoplasmic reticulum (ER) protein translocation channel contains
one nonessential subunit, Sec61β/Sbh1, whose function is poorly understood so far. Its …

Cargo receptors in the endoplasmic reticulum (ER) recognize and help membrane and
soluble proteins along the secretory pathway to reach their location and functional site. We …

Mitochondria are essential organelles of eukaryotic cells and are characterized by their
unique and complex membrane system. They are confined from the cytosol by an envelope …