Clinical metagenomics
CY Chiu, SA Miller - Nature Reviews Genetics, 2019 - nature.com
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …
limited understanding of its clinical pathogenic spectrum of infection and disease …
[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …
encompassing nine members of closely related species that causes tuberculosis in animals …
Plasma miRNA profile at COVID-19 onset predicts severity status and mortality
A Fernández-Pato, A Virseda-Berdices… - Emerging microbes & …, 2022 - Taylor & Francis
Background MicroRNAs (miRNAs) have a crucial role in regulating immune response
against infectious diseases, showing changes early in disease onset and before the …
against infectious diseases, showing changes early in disease onset and before the …
Transcriptomics for child and adolescent tuberculosis
Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …
Sensitive and specific detection of clinical bacteria via vancomycin-modified Fe 3 O 4@ Au nanoparticles and aptamer-functionalized SERS tags
C Zhang, C Wang, R Xiao, L Tang, J Huang… - Journal of Materials …, 2018 - pubs.rsc.org
A sensitive surface-enhanced Raman scattering (SERS) platform for the simultaneous
detection of two pathogenic bacteria on the basis of dual recognition by vancomycin and …
detection of two pathogenic bacteria on the basis of dual recognition by vancomycin and …
Two-step förster resonance energy transfer amplification for ratiometric detection of pathogenic bacteria in food samples
Z Li, H Xu, Q Feng, Z Zhang, X Miao - Food Chemistry, 2023 - Elsevier
We described a two-step förster resonance energy transfer (FRET) system for ratiometric
Staphylococcus aureus (S. aureus) detection based on a dual-recognition proximity binding …
Staphylococcus aureus (S. aureus) detection based on a dual-recognition proximity binding …
Investigating gene expression profiles of whole blood and peripheral blood mononuclear cells using multiple collection and processing methods
Gene expression profiling using blood samples is a valuable tool for biomarker discovery in
clinical studies. Different whole blood RNA collection and processing methods are highly …
clinical studies. Different whole blood RNA collection and processing methods are highly …
Leveraging transcriptomics for precision diagnosis: Lessons learned from cancer and sepsis
M Tsakiroglou, A Evans, M Pirmohamed - Frontiers in Genetics, 2023 - frontiersin.org
Diagnostics require precision and predictive ability to be clinically useful. Integration of multi-
omic with clinical data is crucial to our understanding of disease pathogenesis and …
omic with clinical data is crucial to our understanding of disease pathogenesis and …
A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough
Improved tuberculosis (TB) prevention and control depend critically on the development of a
simple, readily accessible rapid triage test to stratify TB risk. We hypothesized that a blood …
simple, readily accessible rapid triage test to stratify TB risk. We hypothesized that a blood …