Antigen recognition and presentation are highlighted as the first steps in developing
specialized antigen responses. Dendritic cells (DCs) are outstanding professional antigen …

Among the new cancer cases and resulting deaths among women worldwide, breast cancer
is the most significant threat to women's health. In recent years, immunotherapy was initially …

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer
death in women worldwide. Recent advances in the field of immuno-oncology demonstrate …

The two new heterometallic Ru (II)-tpy/ferrocene complexes [Ru (tpy) Cl2 (mtefc)](1) and [Ru
(tpy) Cl2 (mtpfc)](2)(where tpy= 2, 2′: 6′, 2′′-terpyridine, mtefc=(2-(methylthio) ethyl) …

Breast cancer affects roughly one in eight women over their lifetime and is a leading cause
of cancer-related death in women. While outcomes have improved in recent years …

Background In a series of our preclinical studies, we have reported that conditioning of α/β
CD8+ T cells in vitro with interleukin-12 (IL-12) during their expansion improves their homing …

Adoptive cell-based immunotherapy typically utilizes cytotoxic T lymphocytes (CTLs),
expanding these cells ex vivo. Such expansion is traditionally accomplished through the use …

Breast cancer (BC) is the most common malignancy among women–in 2018 alone, 2.1
million new cases were diagnosed worldwide. Advanced BC includes both locally …

Immunotherapy becomes a promising line of treatment for breast cancer (BC) however, its
success rate is still limited. Methods The study was designed to optimize the condition for …

O estágio curricular é a etapa final do nosso percurso académico enquanto estudantes de
Ciências Farmacêuticas, constituindo um elo de ligação entre a realidade académica e …