Advances in T cells based on inflammation in metabolic diseases
With the increasing incidence of metabolic diseases year by year and their impact on the
incidence of cardiovascular diseases, metabolic diseases have attracted great attention as a …
incidence of cardiovascular diseases, metabolic diseases have attracted great attention as a …
Molecular basis of oxidative stress in gouty arthropathy
Y Zamudio-Cuevas, C Hernández-Díaz, C Pineda… - Clinical …, 2015 - Springer
Gout is a disorder of urate metabolism in which persistent high urate levels in the
extracellular fluids result in the deposition of monosodium urate (MSU) crystal in joints and …
extracellular fluids result in the deposition of monosodium urate (MSU) crystal in joints and …
[HTML][HTML] MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
Gout is an autoinflammatory disorder associated with deposition of monosodium urate
(MSU) crystals in joints and periarticular tissues. Recent advances suggest that the innate …
(MSU) crystals in joints and periarticular tissues. Recent advances suggest that the innate …
Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells
MR Nazareth, L Broderick… - The Journal of …, 2007 - journals.aai.org
The tumor microenvironment of human non-small cell lung cancer (NSCLC) is composed
largely of stromal cells, including fibroblasts, yet these cells have been the focus of few …
largely of stromal cells, including fibroblasts, yet these cells have been the focus of few …
Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal–induced murine peritoneal model of acute gout
WJ Martin, M Walton, J Harper - Arthritis & Rheumatism, 2009 - Wiley Online Library
Objective To determine whether infiltrating monocytes, neutrophils, or resident macrophages
contribute to the early inflammatory response to monosodium urate monohydrate (MSU) …
contribute to the early inflammatory response to monosodium urate monohydrate (MSU) …
Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese
Gout is one of the most common types of inflammatory arthritis, caused by the deposition of
monosodium urate crystals in and around the joints. Previous genome-wide association …
monosodium urate crystals in and around the joints. Previous genome-wide association …
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E
Type I interferon is an integral component of the antiviral response, and its production is
tightly controlled at the levels of transcription and translation. The eukaryotic translation …
tightly controlled at the levels of transcription and translation. The eukaryotic translation …
Inducible nitric oxide synthase (iNOS) expression in monocytes during acute Dengue Fever in patients and during in vitro infection
PCF Neves-Souza, EL Azeredo, SMO Zagne… - BMC infectious …, 2005 - Springer
Mononuclear phagocytes are considered to be main targets for Dengue Virus (DENV)
replication. These cells are activated after infection, producing proinflammatory mediators …
replication. These cells are activated after infection, producing proinflammatory mediators …
Monosodium urate monohydrate crystal–recruited noninflammatory monocytes differentiate into M1‐like proinflammatory macrophages in a peritoneal murine model …
Objective To profile monosodium urate monohydrate (MSU) crystal–recruited monocyte
inflammatory function during the course of in vivo differentiation, in a murine model of …
inflammatory function during the course of in vivo differentiation, in a murine model of …
Association between serum uric acid level and peripheral arterial disease
A Shankar, BEK Klein, FJ Nieto, R Klein - Atherosclerosis, 2008 - Elsevier
BACKGROUND: Higher serum uric acid levels have been implicated in the development
and progression of atherosclerotic cardiovascular disease. However, it is not clear whether …
and progression of atherosclerotic cardiovascular disease. However, it is not clear whether …