[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

[HTML][HTML] Pharmacological effects of gallic acid in health and diseases: A mechanistic review

N Kahkeshani, F Farzaei, M Fotouhi… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): Gallic acid is a natural phenolic compound found in several fruits and
medicinal plants. It is reported to have several health-promoting effects. This review aims to …

Probing gallic acid for its broad spectrum applications

S Choubey, S Goyal, LR Varughese… - Mini reviews in …, 2018 - ingentaconnect.com
Gallic acid and its derivatives not only exhibit excellent antioxidant, anticarcinogenic,
antimutagenic, antimicrobial properties but also provide protection to the cells against …

Resveratrol and Alzheimer's disease: mechanistic insights

T Ahmed, S Javed, S Javed, A Tariq, D Šamec… - Molecular …, 2017 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in the elderly and is
characterized by progressive cognitive and memory deficits. The pathological hallmarks of …

Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts

CL Chang, CS Lin - Evidence‐based Complementary and …, 2012 - Wiley Online Library
The objectives of this study were to determine phytochemical compositions,
chemiluminescence antioxidant activities, and neuroprotective effects on PC12 cells for …

Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes

CH Yoon, SJ Chung, SW Lee, YB Park, SK Lee… - Joint Bone Spine, 2013 - Elsevier
OBJECTIVES: To investigate whether gallic acid (3, 4, 5-trihydroxybenzoic acid), a natural
polyphenolic acid found in gall nuts, sumac, oak bark, tea leaves, grapes and wine, has pro …

Phenolic characterization and neuroprotective properties of grape pomace extracts

A Chiavaroli, M Balaha, A Acquaviva, C Ferrante… - Molecules, 2021 - mdpi.com
Vitis vinifera (grape) contains various compounds with acknowledged phytochemical and
pharmacological properties. Among the different parts of the plant, pomace is of particular …

Gallic acid induces apoptosis in A375. S2 human melanoma cells through caspase-dependent and-independent pathways

C Lo, TY Lai, JH Yang, JS Yang… - International …, 2010 - spandidos-publications.com
The natural antioxidant gallic acid (GA) has demonstrated a significant inhibition of cell
proliferation and induction of apoptosis in a series of cancer cell lines. However, there is no …

Antioxidant activity of fucoidan modified with gallic acid using the redox method

KDCM de Melo, LS Lisboa, MF Queiroz, WS Paiva… - Marine Drugs, 2022 - mdpi.com
Antioxidant compounds decrease the amount of intracellular reactive oxygen species (ROS)
and, consequently, reduce the deleterious effects of ROS in osteoblasts. Here, we modified …

Gallic acid induces G0/G1 phase arrest and apoptosis in human leukemia HL-60 cells through inhibiting cyclin D and E, and activating mitochondria-dependent …

RD Yeh, JC Chen, TY Lai, JS Yang, CS Yu… - Anticancer …, 2011 - ar.iiarjournals.org
Gallic acid (GA) induces apoptosis in different types of cancer cell lines. In this study, we
investigate the apoptotic effects induced by GA in human promyelocytic leukemia HL-60 …