TAR DNA binding protein 43 (TDP-43) is a versatile RNA/DNA binding protein involved in
RNA-related metabolism. Hyper-phosphorylated and ubiquitinated TDP-43 deposits act as …

Stress granules are ribonucleoprotein assemblies that form in response to cellular stress.
Many of the RNA-binding proteins found in stress granule proteomes contain prion-like …

Prions are self‐perpetuating proteins able to switch between a soluble state and an
aggregated‐and‐transmissible conformation. These proteinaceous entities have been …

Proteins bearing prion-like domains (PrLDs) are essential players in stress granules (SG)
assembly. Analysis of data on heat stress-induced recruitment of yeast PrLDs to SG …

Background Around 1% of human proteins are predicted to contain a disordered and low
complexity prion-like domain (PrLD). Mutations in PrLDs have been shown promote a …

Prion-like behavior has been in the spotlight since it was first associated with the onset of
mammalian neurodegenerative diseases. However, a growing body of evidence suggests …

Human prion-like proteins often correspond to nucleic acid binding proteins, displaying both
globular domains and long intrinsically disordered regions (IDRs)(Harrison and Shorter …

Considerable advances in understanding the protein features favoring prion formation in
yeast have facilitated the development of effective yeast prion prediction algorithms. Here …

Human prion-like proteins often correspond to nucleic acid binding proteins, displaying both
globular domains and long intrinsically disordered regions (IDRs)(Harrison and Shorter …