The pandemic threat of emerging H5 and H7 avian influenza viruses

TC Sutton - Viruses, 2018 - mdpi.com
The 1918 H1N1 Spanish Influenza pandemic was the most severe pandemic in modern
history. Unlike more recent pandemics, most of the 1918 H1N1 virus' genome was derived …

Pandemic potential of highly pathogenic avian influenza clade 2.3. 4.4 A (H5) viruses

R Yamaji, MD Saad, CT Davis… - Reviews in Medical …, 2020 - Wiley Online Library
The panzootic caused by A/goose/Guangdong/1/96‐lineage highly pathogenic avian
influenza (HPAI) A (H5) viruses has occurred in multiple waves since 1996. From 2013 …

Co-existence and co-infection of influenza A viruses and coronaviruses: Public health challenges

J Yang, Y Gong, C Zhang, J Sun, G Wong, W Shi, W Liu… - The Innovation, 2022 - cell.com
Since the 20 th century, humans have lived through five pandemics caused by influenza A
viruses (IAVs)(H1N1/1918, H2N2/1957, H3N2/1968, and H1N1/2009) and the coronavirus …

A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential

C Grund, D Hoffmann, R Ulrich, M Naguib… - Emerging microbes & …, 2018 - Taylor & Francis
We investigated in a unique setup of animal models and a human lung explant culture
biological properties, including zoonotic potential, of a representative 2016 highly …

HA N193D substitution in the HPAI H5N1 virus alters receptor binding affinity and enhances virulence in mammalian hosts

SG Jang, YI Kim, MAB Casel, JH Choi… - Emerging Microbes & …, 2024 - Taylor & Francis
ABSTRACT During the 2021/2022 winter season, we isolated highly pathogenic avian
influenza (HPAI) H5N1 viruses harbouring an amino acid substitution from Asparagine (N) to …

Pathogenicity and genomic changes of a 2016 European H5N8 highly pathogenic avian influenza virus (clade 2.3. 4.4) in experimentally infected mallards and …

C Leyson, S Youk, D Smith, K Dimitrov, DH Lee… - Virology, 2019 - Elsevier
Highly pathogenic avian influenza H5N8 clade 2.3. 4.4 virus caused outbreaks in poultry
and unusually high mortality in wild birds in 2016–2017. The pathobiology of one of these …

Avian influenza: strategies to manage an outbreak

A Simancas-Racines, S Cadena-Ullauri… - Pathogens, 2023 - mdpi.com
Avian influenza (AI) is a contagious disease among the poultry population with high avian
mortality, which generates significant economic losses and elevated costs for disease …

[HTML][HTML] Risk assessment for highly pathogenic avian influenza A (H5N6/H5N8) clade 2.3. 4.4 viruses

CHT Bui, DIT Kuok, HW Yeung, KC Ng… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
The numerous global outbreaks and continuous reassortments of highly pathogenic avian
influenza (HPAI) A (H5N6/H5N8) clade 2.3. 4.4 viruses in birds pose a major risk to the …

Genetic diversity, phylogeography, and evolutionary dynamics of highly pathogenic avian influenza A (H5N6) viruses

J Zhang, Y Chen, N Shan, X Wang, S Lin, K Ma… - Virus …, 2020 - academic.oup.com
From 2013 onwards, the spread of novel H5N6 highly pathogenic avian influenza (HPAI)
viruses in China has posed great threats to not only poultry industry but also human health …

The genetics of highly pathogenic avian influenza viruses of subtype H5 in Germany, 2006–2020

J King, T Harder, FJ Conraths, M Beer… - Transboundary and …, 2021 - Wiley Online Library
Abstract The H5 A/Goose/Guangdong/1/1996 (gs/GD) lineage emerged in China in 1996.
Rooted in the respective gs/GD lineage, the hemagglutinin (HA) gene of highly pathogenic …