Scorpion toxins have been the subject of many studies exploring their pharmacological
potential. The high affinity and the overall selectivity to various types of ionic channels …

Scorpions are incredible venomous animals found on almost every continent. According to
fossil data, these animals have been able to adapt to the different environments from the …

Spider venoms include various peptide toxins that modify the ion currents, mainly of
excitable insect cells. Consequently, scientific research on spider venoms has revealed a …

A fundamental issue of the characterization of single-chain variable fragments (scFvs),
capable of neutralizing scorpion toxins, is their cross-neutralizing ability. This aspect is very …

The recombinant antibody fragments generated against the toxic components of scorpion
venoms are considered a promising alternative for obtaining new antivenoms for therapy …

The growing resistance of insects to chemical pesticides is reducing the effectiveness of
conventional methods for pest control and thus, the development of novel insecticidal agents …

Mature Ts1, the main neurotoxin from Tityus serrulatus venom, has its C-terminal Cys
amidated, while the isolated isoform of Ts1, named Ts1-G, keeps the non-amidated Gly …

New approaches aimed at neutralizing the primary toxic components present in scorpion
venoms, represent a promising alternative to the use of antivenoms of equine origin in …

The objective of this study was to characterize six different scorpion venoms using biological
and biochemical methods, including a preliminary MS/MS and a post-translational …

We identified Tf2, the first β-scorpion toxin from the venom of the Brazilian scorpion Tityus
fasciolatus. Tf2 is identical to Tb2-II found in Tityus bahiensis. We found that Tf2 selectively …