Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses

K Seong, KV Krasileva - Nature Microbiology, 2023 - nature.com
Elucidating the similarity and diversity of pathogen effectors is critical to understand their
evolution across fungal phytopathogens. However, rapid divergence that diminishes …

Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity

D Del Corpo, D Coculo, M Greco, G De Lorenzo… - Plant …, 2024 - cell.com
The apoplast is one of the first cellular compartments outside the plasma membrane that
phytopathogenic microbes encounter in the early stages of plant tissue invasion. Plants …

Seeking the interspecies crosswalk for filamentous microbe effectors

N Stuer, P Van Damme, S Goormachtig… - Trends in Plant …, 2023 - cell.com
Both pathogenic and symbiotic microorganisms modulate the immune response and
physiology of their host to establish a suitable niche. Key players in mediating colonization …

Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector

R Zdrzałek, Y Xi, T Langner, AR Bentham… - Proceedings of the …, 2024 - pnas.org
Bioengineering of plant immune receptors has emerged as a key strategy for generating
novel disease resistance traits to counteract the expanding threat of plant pathogens to …

A pathogen effector FOLD diversified in symbiotic fungi

A Teulet, C Quan, E Evangelisti, A Wanke… - New …, 2023 - Wiley Online Library
Pathogenic fungi use secreted effector proteins to suppress immunity and support their
infection, but effectors have also been reported from fungi that engage in nutritional …

The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies

SY Daniel, MA Outram, A Smith, CL McCombe… - elife, 2024 - elifesciences.org
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside
plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors …

A global pangenome for the wheat fungal pathogen Pyrenophora tritici-repentis and prediction of effector protein structural homology

PM Moolhuijzen, PT See, G Shi… - Microbial …, 2022 - microbiologyresearch.org
The adaptive potential of plant fungal pathogens is largely governed by the gene content of
a species, consisting of core and accessory genes across the pathogen isolate repertoire …

Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences

R Müller, A König, S Groth, R Zarnowski, C Visser… - Nature …, 2024 - nature.com
The opportunistic fungal pathogen Candida albicans damages host cells via its peptide
toxin, candidalysin. Before secretion, candidalysin is embedded in a precursor protein …

The Role of Tox Effector Proteins in the Parastagonospora Nodorum–Wheat Interaction

MC McDonald, SJ Williams, PS Solomon - Plant Relationships: Fungal …, 2022 - Springer
Parastagonospora nodorum is the causal agent of the glume blotch disease on wheat and is
responsible for significant yield losses globally. Despite its importance, the mechanisms …

[HTML][HTML] Effectors: key actors in phytopathology

JNA Todd, KG Carreón-Anguiano… - Revista mexicana de …, 2023 - scielo.org.mx
Effectors are small molecules, mostly proteins, produced by microorganisms that use them to
interact with their hosts. Regarding plant hosts, effectors suppress plant immunity by …