Malaria still poses one of the most serious threats to human health worldwide and the
prevailing lack of effective, clinically licensed, vaccines means that prophylaxis and …

Plasmodium vivax is the most prevalent malarial species in South America and exerts a
substantial burden on the populations it affects. The control and eventual elimination of P …

Background The study of reverse evolution from resistant to susceptible phenotypes can
reveal constraints on biological evolution, a topic for which evolutionary theory has relatively …

Background Plasmodium vivax is the predominant species of human malaria parasites
present in China. Although sulphadoxine-pyrimethamine (SP) and chloroquine (CQ) have …

Plasmodium vivax is the predominant species of the human malaria parasite present in the
Indian subcontinent. There have been recent reports on Chloroquine (CQ) resistance and …

Background The increasing antimalarial drug resistance is a significant hindrance to malaria
control and elimination programs. For the last six decades, chloroquine (CQ) plus …

In Iran, both Plasmodium vivax and P. falciparum malaria have been detected, but P. vivax is
the predominant species. Point mutations in dihydrofolate reductase (dhfr) gene in both …

The analysis of prevalence and distribution of pvdhfr and pvdhps mutations were performed
in 169 samples collected from patients with Plasmodium vivax infection who attended the …

Molecular analysis of antifolate resistance-associated genes—dihydrofolate reductase (dhfr)
and dihydropteroate synthetase (dhps) of Plasmodium vivax is important in predicting the …

Background: The aim of this review was to describe the application of molecular methods in
epidemiological aspects of malaria vectors, parasites, and human hosts in Iran and their …