Biofilms: Survival and defense strategy for pathogens

A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …

[HTML][HTML] The role of functional amyloids in bacterial virulence

N Van Gerven, SE Van der Verren, DM Reiter… - Journal of molecular …, 2018 - Elsevier
Amyloid fibrils are best known as a product of human and animal protein misfolding
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …

Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals

A Taglialegna, S Navarro, S Ventura, JA Garnett… - PLoS …, 2016 - journals.plos.org
Biofilms are communities of bacteria that grow encased in an extracellular matrix that often
contains proteins. The spatial organization and the molecular interactions between matrix …

General overview on nontuberculous mycobacteria, biofilms, and human infection

S Faria, I Joao, L Jordao - Journal of pathogens, 2015 - Wiley Online Library
Nontuberculous mycobacteria (NTM) are emergent pathogens whose importance in human
health has been growing. After being regarded mainly as etiological agents of opportunist …

[HTML][HTML] The extracellular matrix of mycobacterial biofilms: could we shorten the treatment of mycobacterial infections?

P Chakraborty, A Kumar - Microbial cell, 2019 - ncbi.nlm.nih.gov
A number of non-tuberculous mycobacterium species are opportunistic pathogens and
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …

[HTML][HTML] Functional amyloid and other protein fibers in the biofilm matrix

E Erskine, CE MacPhee, NR Stanley-Wall - Journal of Molecular Biology, 2018 - Elsevier
Biofilms are ubiquitous in the natural and man-made environment. They are defined as
microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing …

Bacterial biofilms in the human body: Prevalence and impacts on health and disease

EK Perry, MW Tan - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Bacterial biofilms can be found in most environments on our planet, and the human body is
no exception. Consisting of microbial cells encased in a matrix of extracellular polymers …

Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis

DF Ackart, L Hascall-Dove, SM Caceres… - Pathogens and …, 2014 - academic.oup.com
There is an urgent need to improve methods used to screen antituberculosis drugs. An in
vitro assay was developed to test drug treatment strategies that specifically target drug …

Microbial composition and antibiotic resistance of biofilms recovered from endotracheal tubes of mechanically ventilated patients

I Vandecandelaere, T Coenye - Biofilm-based Healthcare-associated …, 2014 - Springer
In critically ill patients, breathing is impaired and mechanical ventilation, using an
endotracheal tube (ET) connected to a ventilator, is necessary. Although mechanical …

Fold modulating function: bacterial toxins to functional amyloids

AK Syed, BR Boles - Frontiers in microbiology, 2014 - frontiersin.org
Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is
well known that environmental factors control toxin expression, however, recent work …